| | Chloromethyl ethyl ether Basic information |
| | Chloromethyl ethyl ether Chemical Properties |
| Melting point | -104°C | | Boiling point | 82 °C(lit.) | | density | 1.019 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.404(lit.) | | Fp | 67 °F | | storage temp. | 0-6°C | | solubility | Chloroform (Soluble), Ethyl Acetate (Slightly) | | form | Liquid | | color | Clear colorless to pale yellow | | Specific Gravity | 1.019 | | InChI | InChI=1S/C3H7ClO/c1-2-5-3-4/h2-3H2,1H3 | | InChIKey | FCYRSDMGOLYDHL-UHFFFAOYSA-N | | SMILES | CCOCCl | | CAS DataBase Reference | 3188-13-4(CAS DataBase Reference) | | NIST Chemistry Reference | Ethane, (chloromethoxy)-(3188-13-4) | | EPA Substance Registry System | Ethane, (chloromethoxy)- (3188-13-4) |
| | Chloromethyl ethyl ether Usage And Synthesis |
| Chemical Properties | clear colorless to pale yellow liquid | | Uses | Chloromethyl ethyl ether can be used to prepare:
- 6-Benzyl-1-(ethoxymethyl)-5-iodopyrimidine-2,4(1H,3H)-dione, a key intermediate in the preparation of MKC-442 analog.
- Acylation catalyst for alcohols named 1,3-bis-[(R)-1-(2-naphthyl)ethyl]imidazoliumchloride by reacting with glyoxal-bis-[(R)-1-(2-naphthyl)ethyl]imine.
| | General Description | A colorless liquid. Slightly denser than water and insoluble in water. Flash point below 73°F. May be moderately toxic by ingestion, inhalation or skin absorption. Severely irritates skin, eyes and mucous membranes. | | Air & Water Reactions | Highly flammable. Insoluble in water. | | Reactivity Profile | Chloromethyl ethyl ether tends to form unstable peroxides when exposed to oxygen or air. These products can sometimes be observed as clear crystals deposited on containers or along the surface of the liquid. Forms salts with strong acids and addition complexes with Lewis acids. May react violently with strong oxidizing agents. I | | Health Hazard | TOXIC; may be fatal if inhaled, ingested or absorbed through skin. Inhalation or contact with some of these materials will irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution. | | Fire Hazard | HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion and poison hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water. |
| | Chloromethyl ethyl ether Preparation Products And Raw materials |
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