Flopropione

Flopropione Basic information
Product Name:Flopropione
Synonyms:1-(2,4,6-trihydroxyphenyl)-1-propanon;1-(2,4,6-Trihydroxyphenyl)-1-propanone;13907 R. P.;13907r.p.;Argobroda;Flopropione Phlopropiophenone;1-(2,4,6-trihydroxyphenyl)propanone;1-Propanone, 1-(2,4,6-trihydroxyphenyl)-
CAS:2295-58-1
MF:C9H10O4
MW:182.17
EINECS:218-942-8
Product Categories:Aromatic Propiophenones (substituted)
Mol File:2295-58-1.mol
Flopropione Structure
Flopropione Chemical Properties
Melting point 177°C
Boiling point 275.56°C (rough estimate)
density 1.2481 (rough estimate)
refractive index 1.4500 (estimate)
storage temp. Inert atmosphere,Room Temperature
solubility Soluble in DMSO
pka7.49±0.45(Predicted)
form powder to crystal
color White to Orange to Green
Merck 14,4106
LogP2.600 (est)
CAS DataBase Reference2295-58-1(CAS DataBase Reference)
NIST Chemistry ReferenceFlopropione(2295-58-1)
EPA Substance Registry System1-Propanone, 1-(2,4,6-trihydroxyphenyl)- (2295-58-1)
Safety Information
Risk Statements 36/37/38
Safety Statements 26-36/37/39
RTECS UH4429100
HS Code 2914.50.3000
MSDS Information
Flopropione Usage And Synthesis
Usesantispasmodic
PreparationPreparation by reaction of propionitrile with phlo-roglucinol (Hoesch reaction);
Preparation by reaction of propionic anhydride with phloroglucinol
in the presence of concentrated sulfuric acid (one drop) at 130° for 5 min ? (65%)
in the presence of Amberlite IR-120 (cation exchange resin sulfonic acid ? type) at 160° for 2–3 h (42%). N.B.: Zeokarb 225 was found to be as effective
in the presence of boron trifluoride etherate at 10° (62–65%)
Preparation by reaction of propionyl chloride with phloroglucinol
in the presence of aluminium chloride in nitrobenzene/carbon disulfide ? solution (76%), in nitrobenzene at 60° (55%) or without solvent at 50° (70%)
in the presence of boron trifluoride etherate at 10° (compound ? 3) (62–65%).






DefinitionChEBI: Flopropione is an organic molecular entity.
Flopropione Preparation Products And Raw materials
Phenylfluorone Acetylacetone Propane DIPHENYLCYCLOPROPENONE Phenylacetone Trimethylolpropane Calcium pyruvate Pyruvic acid Benzoylcyclohexane Flopropione 4'-Hydroxyacetophenone 3'-Hydroxypropiophenone Tris(hydroxymethyl)aminomethane 2'-Hydroxyacetophenone Propiophenone Triphenylphosphine Diphenylsilanediol Diacetone Alcohol

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