ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Piperazine compounds TRANS-1-CINNAMYLPIPERAZINE

TRANS-1-CINNAMYLPIPERAZINE

TRANS-1-CINNAMYLPIPERAZINE Basic information
Product Name:TRANS-1-CINNAMYLPIPERAZINE
Synonyms:1-TRANS-CINNAMYL PIPERAZINE;1-((E)-3-PHENYLALLYL)PIPERAZINE;1-(CINNAMYL)PIPERAZINE;1-(3-PHENYL-ALLYL)-PIPERAZINE;LABOTEST-BB LT00233225;N-CINNAMYLPIPERAZINE;1-(Cinnamyl)piperazine 97%;TIMTEC-BB SBB000411
CAS:18903-01-0
MF:C13H18N2
MW:202.3
EINECS:242-652-0
Product Categories:Pharmaceutical Intermediates;Piperidines, Piperidones, Piperazines
Mol File:18903-01-0.mol
TRANS-1-CINNAMYLPIPERAZINE Structure
TRANS-1-CINNAMYLPIPERAZINE Chemical Properties
Melting point 39-44 °C(lit.)
Boiling point 129 °C1 mm Hg(lit.)
density 0.989 g/mL at 25 °C(lit.)
refractive index 1.574-1.576
Fp >230 °F
pka9.17±0.10(Predicted)
Specific Gravity0.989
CAS DataBase Reference18903-01-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
HS Code 29335995
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
TRANS-1-CINNAMYLPIPERAZINE Usage And Synthesis
Descriptiontrans-1-Cinnamylpiperazine is a piperazine derivative. It was used as a test compound to investigate the in vitro efficacy as an antiprotozoal against Philasterides dicentrarchi. It may be used to synthesize Incentrom A derivatives.
Chemical Propertiesclear colorless to yellow liquid after melting
Uses1-Cinnamylpiperazine is a useful building block and a metabolite of Flunarizine (F455200), which is a selective calcium entry blocker used for prophylaxis of severe refractory migraine and symptomatic treatment of vestibular vertigo.
TRANS-1-CINNAMYLPIPERAZINE Preparation Products And Raw materials
Raw materialsPiperazine-->1-Piperazinecarbaldehyde
N-PHENYL(4-(3-PHENYLPROP-2-ENYL)PIPERAZINYL)FORMAMIDE N-(4-CHLOROPHENYL)(4-(3-PHENYLPROP-2-ENYL)PIPERAZINYL)FORMAMIDE 1-(4-BROMOPHENYL)-3-[4-(3-PHENYL-2-PROPENYL)PIPERAZINO]DIHYDRO-1H-PYRROLE-2,5-DIONE (E)-3-(4-CINNAMYLPIPERAZIN-1-YL)-1-(4-FLUOROPHENYL)PYRROLIDINE-2,5-DIONE CINNAMYL PIEPRAZINE HYDROCHLORIDE 3,5-DINITROPHENYL 4-(3-PHENYLPROP-2-ENYL)PIPERAZINYL KETONE 1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYL-2-PROPENYL)-PIPERAZINE DIHYDROCHLORIDE 1,4-DICHLORO-2-((4-(3-PHENYLPROP-2-ENYL)PIPERAZINYL)SULFONYL)BENZENE 4-CHLORO-1-((4-(3-PHENYLPROP-2-ENYL)PIPERAZINYL)SULFONYL)BENZENE Stugeron TRANS-1-CINNAMYLPIPERAZINE 4-[3-(4-METHYLPIPERAZINO)-3-OXO-1-PROPENYL]BENZENECARBONITRILE 1-(2-(BIS-(4-FLUOROPHENYL)METHOXY)ETHYL)-4-(3-PHENYL-2-PROPENYL)PIPERAZINE DIHYDROCHLORIDE 1-(4-(3-PHENYLPROP-2-ENYL)PIPERAZINYL)HEXAN-1-ONE (E)-3-(4,5-dimethoxy-2-nitrophenyl)-1-(4-methylpiperazino)-2-propen-1-one 2-((4-(3-PHENYLPROP-2-ENYL)PIPERAZINYL)CARBONYL)CYCLOHEXANECARBOXYLIC ACID 4-(3-PHENYLPROP-2-ENYL)-1-(PHENYLSULFONYL)PIPERAZINE trans-1-Cinnamylpiperazine
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