|
| | 2-Ethyl-5,7-diMethyl-3H-iMidazo[4,5-b]pyridine Basic information |
| Product Name: | 2-Ethyl-5,7-diMethyl-3H-iMidazo[4,5-b]pyridine | | Synonyms: | 2-ETHYL-5,7-DIMETHYL-3H-IMIDAZO[4,5-B]PYRIDINE;1H-IMIDAZO[4,5-B]PYRIDINE, 2-ETHYL-5,7-DIMETHYL-;2-ethyl-5,7-dimethyl-1H-imidazo[4,5-b]pyridine;5,7-DiMethyl-2-ethyliMidazo[4,5-b]pyridine;2-Ethyl-5,7-Dimethyl-3H-Imidazo[4,5-B]Pyridine(WX690021);2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-β]pyridine;3H-Imidazo[4,5-b]pyridine, 2-ethyl-5,7-dimethyl-;2-Ethyl-5,7-diMethyl-3H-iMidazo[4,5-b]pyridine ISO 9001：2015 REACH | | CAS: | 133240-06-9 | | MF: | C10H13N3 | | MW: | 175.23 | | EINECS: | | | Product Categories: | Aromatics Compounds;Aromatics;Bases & Related Reagents;Heterocycles;Nucleotides;various pyridine derivatives;Pyridine Derivatives | | Mol File: | 133240-06-9.mol | ![2-Ethyl-5,7-diMethyl-3H-iMidazo[4,5-b]pyridine Structure](CAS/GIF/133240-06-9.gif) |
| | 2-Ethyl-5,7-diMethyl-3H-iMidazo[4,5-b]pyridine Chemical Properties |
| Melting point | 142-146 °C | | Boiling point | 279.7±23.0 °C(Predicted) | | density | 1.18±0.1 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | solubility | DMSO, Methanol | | pka | 8.89±0.40(Predicted) | | form | Solid | | color | Pale Yellow |
| | 2-Ethyl-5,7-diMethyl-3H-iMidazo[4,5-b]pyridine Usage And Synthesis |
| Description | 2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine is a nonpeptidic angiotensin II receptor antagonist whose imidazo[4,5-b]pyridine scaffold has been used to examine a variety of positional substitutions in the development of orally active, long duration antihypertensive agents. | | Chemical Properties | Off-white powder | | Uses | 2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine is used as building block in chemical synthesis. Attributes Development Product Contact | | Uses | 2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine (cas# 133240-06-9) is a compound useful in organic synthesis. | | Synthesis Reference(s) | Tetrahedron Letters, 35, p. 5775, 1994 DOI: 10.1016/S0040-4039(00)78181-0 | | in vitro | in a previous study, 2-ethyl-5,7-dimethyl-3h-imidazo[4,5-b]pyridine was synthezed by reduction of 2-amino-3-nitropyridine derivatives to the corresponding diaminopyridine which was then condensed with an appropriate carboxylic acid in polyphosphoric acid. in vitro activity study showed that 2-ethyl-5,7-dimethyl-3h-imidazo[4,5-b]pyridine was a nonpeptidic angiotensin ii receptor antagonist whose imidazo[4,5-b]pyridine scaffold had been used to examine plenty of positional substitutions in the development of orally active, long duration antihypertensive agents [1]. | | references | [1] mantlo, n. b.,chakravarty, p.k.,ondeyka, d.l., et al. potent, orally active imadazo[4,5-b]pyridine-based angiotensin ii receptor antagonists. journal of medicinal chemistry 34(9), 2919-2922 (1991). |
| | 2-Ethyl-5,7-diMethyl-3H-iMidazo[4,5-b]pyridine Preparation Products And Raw materials |
|
