7-METHYLGUANOSINE

7-METHYLGUANOSINE Basic information
Product Name:7-METHYLGUANOSINE
Synonyms:2-aMino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-7-Methyl-6-oxo-6,7-dihydro-1H-purin-9-iuM;2-amino-6,9-dihydro-7-methyl-6-oxo-9-1H-Purinium;2-Amino-6,9-dihydro-7-methyl-6-oxo-9-β-D-ribofuranosyl-1H-purin-7-ium;2-Amino-6-oxo-7-methyl-9-(β-D-ribofuranosyl)-1,6-dihydro-9H-purine-7-ium;N(7)-Methylguanosine;N7-Methylguanosine;1H-Purinium, 2-amino-6,9-dihydro-7-methyl-6-oxo-.beta.-D-ribofuranosyl-;Aids024328
CAS:20244-86-4
MF:C11H15N5O5
MW:297.27
EINECS:
Product Categories:Biochemicals and Reagents;Nucleoside Analogs;Nucleosides, Nucleotides, Oligonucleotides
Mol File:20244-86-4.mol
7-METHYLGUANOSINE Structure
7-METHYLGUANOSINE Chemical Properties
storage temp. 2-8°C
solubility 0.1 M HCl: 10 mg/ml; DMSO: 10 mg/ml
form A crystalline solid
BRN 3713683
Stability:Hygroscopic
InChIKeyOGHAROSJZRTIOK-KQYNXXCUSA-N
Safety Information
Safety Statements 22-24/25
WGK Germany 3
10
HS Code 29349990
MSDS Information
7-METHYLGUANOSINE Usage And Synthesis
Chemical PropertiesWhite powder
Uses7-Methylguanosine has been used in the removal of residual phosphates from pre rigor solution, phosphate mop system and phosphorous standard solution.
DefinitionChEBI: A positively charged methylguanosine in which a single methyl substituent is located at position 7.
General Description7-Methylguanosine structure is also referred to as a cap. It is located on the 5′ end of the cytoplasmic mRNA.
Biochem/physiol Actions7-Methylguanosine is involved in the processing of a cap-dependent translational process of mRNA. It is also involved in protecting the mRNA from degradation due to ribonucleases and mediate nuclear export. 7-Methylguanosine also permits the recruitment of ribosome.
7-METHYLGUANOSINE Preparation Products And Raw materials
Raw materialsDimethyl sulfate-->Iodomethane-->Guanosine
Preparation Products7-METHYLGUANINE
Polyadenosinic acid (Poly A) 5-METHYLCYTOSINE Guanosine 5'-monophosphate disodium salt 7,8-Dihydro-7-methylguanosine

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