ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Proline derivatives N-Boc-D-proline

N-Boc-D-proline

N-Boc-D-proline Basic information
Product Name:N-Boc-D-proline
Synonyms:(R)-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER;T-BUTYLOXYCARBONYL-D-PROLINE;N-ALPHA-TERT-BUTYLOXYCARBONYL-D-PROLINE;N-ALPHA-T-BUTYLOXYCARBONYL-D-PROLINE;N-ALPHA-T-BUTYLOXYCARBONYL-D-PYRROLIDINE-2-CARBOXYLIC ACID;N-ALPHA-T-BOC-D-PROLINE;BOC-(R)-PYRROLIDINE-5-CARBOXYLIC ACID;BOC-D-PROLINE
CAS:37784-17-1
MF:C10H17NO4
MW:215.25
EINECS:1533716-785-6
Product Categories:Amino Acids (N-Protected);Biochemistry;Proline [Pro, P];Boc-Amino Acids and Derivative;Boc-Amino Acids;Boc-Amino acid series;Protected Amino Acids;Pyrrole&Pyrrolidine&Pyrroline;Amino Acids
Mol File:37784-17-1.mol
N-Boc-D-proline Structure
N-Boc-D-proline Chemical Properties
Melting point 134-137 °C (lit.)
alpha 60 º (c=2, acetic acid)
Boiling point 355.52°C (rough estimate)
density 1.1835 (rough estimate)
refractive index 60 ° (C=2, AcOH)
storage temp. 2-8°C
solubility almost transparency in Acetic acid
pka4.01±0.20(Predicted)
form Crystalline Powder or Crystals
color White to off-white
optical activity[α]22/D +60°, c = 2 in acetic acid
BRN 479316
InChIKeyZQEBQGAAWMOMAI-SSDOTTSWSA-N
CAS DataBase Reference37784-17-1(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
WGK Germany 3
HS Code 2933 99 80
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
N-Boc-D-proline Usage And Synthesis
Chemical PropertiesWhite to off-white microcrystalline powder
Usestert-Butoxycarbonyl-D-proline is Boc protected D-proline (P755990). It is used to prepare trichostatin A and trapoxin B analogs as histone deacetylase inhibitors. It is also used to prepare potent and selective nonpeptide inhibitors of caspases 3 and 7.
BOC-PYR-OH DCHA N-Boc-cis-4-Hydroxy-L-proline methyl ester N-Boc-trans-4-Hydroxy-L-proline methyl ester D-Proline (2S,4R)-FMOC-4-AMINO-1-BOC-PYRROLIDINE-2-CARBOXYLIC ACID N-Boc-cis-4-Fmoc-Amino-L-proline BOC-D-PROLINE METHYL ESTER,N-BOC-D-PROLINE METHYL ESTER,BOC-D-PROLINE METHYLESTER LIQUID N-Boc-D-proline BOC-OIC-OH Boc-Hyp-OH BOC-L-PROLINE 4-NITROPHENYL ESTER BOC-HYP(BZL)-OH N-Boc-D-proline BOC-HYP-OBZL BOC-L-PRO-O-CH2-PHI-CH2-COOH BOC-HYP-OH DCHA ALPHA,ALPHA-Dimethyl-3,5-dimethoxybenzyloxycarbonyl-L-proline BOC-L-PROLINE N-HYDROXYSUCCINIMIDE ESTER,BOC-L-PROLINE HYDROXYSUCCINIMIDE ESTER,BOC-L-PROLINE HYDROXYSUCCINIMIDESTER,N-Boc-L-Proline succinimidyl ester
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