BETA-ESTRADIOL 17-ACETATE

BETA-ESTRADIOL 17-ACETATE Basic information
Product Name:BETA-ESTRADIOL 17-ACETATE
Synonyms:1,3,5(10)-ESTRATRIEN-3,17BETA-DIOL 17-ACETATE;1,3,5[10]-ESTRATRIENE-3,17BETA-DIOL 17-ACETATE;17-BETA-ESTRADIOL 17-ACETATE;3,17BETA-DIHYDROXY-1,3,5[10]-ESTRATRIENE 17-ACETATE;BETA-ESTRADIOL 17-ACETATE;B-ESTRADIOL 17-ACETATE;17BETA-ESTRADIOL 17-ACETATE VETRANAL100;Estradiol acetate
CAS:1743-60-8
MF:C20H26O3
MW:314.42
EINECS:605-722-5
Product Categories:Steroids;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;APIs
Mol File:1743-60-8.mol
BETA-ESTRADIOL 17-ACETATE Structure
BETA-ESTRADIOL 17-ACETATE Chemical Properties
Melting point 210 °C
Boiling point 450.5±45.0 °C(Predicted)
density 1.18±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer, Under inert atmosphere
solubility Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly), DMSO (Slightly)
form neat
pka10.26±0.60(Predicted)
color White to Off-White
PH6.96 at 24.1℃ and 10g/L
BRN 2625732
LogP4 at 25℃ and pH5
Safety Information
Hazard Codes T
Risk Statements 60-61
Safety Statements 53-45
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
BETA-ESTRADIOL 17-ACETATE Usage And Synthesis
Chemical PropertiesWhite Solid
UsesProtected Estradiol. Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.
Usesβ-Estradiol 17-acetate has been used in body burden analyses, to study the effect of triclosan on an estuarine fish.
DefinitionChEBI: Beta-Estradiol 17-acetate is a steroid ester.
Brand nameFemring(Galen); Femtrace (Warner Chilcott).
Biochem/physiol Actionsβ-Estradiol is a steroid hormone involved in a number of organ functions. It is significantly associated with brain functions including neuroprotection, neurogenesis and synaptic plasticity. β-Estradiol maintains bone homeostasis, and hence is preferred for osteoporosis therapy. 17-β-Estradiol is the most active estrogen generated in our body. During postmenopausal, 17-β-estradiol inhibits oxidative modification in low density lipoprotein. This indicates that estrogen replacement therapy might be useful in treating cardiovascular disease.
BETA-ESTRADIOL 17-ACETATE Preparation Products And Raw materials
Estradiol valerate Estradiol 17-Octadecanoate-1-14C 1,3,5(10)-ESTRATRIEN-3,17-BETA-DIOL DIBENZOATE Estradiol-3-benzoate-17-butyrate 1,3,5(10)-ESTRATRIEN-3,15-ALPHA, 16-ALPHA, 17-BETA-TETROL TETRA ACETATE Oestradiol 17-heptanoate beta-Estradiol 17-propionate Estradiol diacetate ESTRADIOL 17-O-OCTADECANOATE 1,3,5(10)-ESTRATRIEN-3,17-ALPHA-DIOL-6-ONE DIACETATE 1,3,5(10)-ESTRATRIEN-3,17-BETA-DIOL DICYCLOPENTYLPROPIONATE BETA-ESTRADIOL 17-ACETATE 17-BETA-ESTRADIOL 3,17-DIPROPIONATE 1,3,5(10)-ESTRATRIEN-3,17-BETA-DIOL DIHEMSUCCINATE 17-BETA-ESTRADIOL 17-ACETATE, 3-METHYL ETHER ESTRIOL TRIACETATE Estriol 16,17-diacetate Estradiol Cypionate

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