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| | CB-1158 Basic information |
| Product Name: | CB-1158 | | Synonyms: | (3R,4S)-1-(L-alanyl)-3-amino-4-(3-boronopropyl)pyrrolidine-3-carboxylic acid;INCB01158;3-Pyrrolidinecarboxylic acid, 3-amino-1-[(2S)-2-amino-1-oxopropyl]-4-(3-boronopropyl)-, (3R,4S)-;Numidargistat (CB1158, INCB01158);Numidargistat 2HCl (CB1158, INCB01158);Numidargistat | | CAS: | 2095732-06-0 | | MF: | C11H22BN3O5 | | MW: | 287.12 | | EINECS: | | | Product Categories: | pyrolidine | | Mol File: | 2095732-06-0.mol |  |
| | CB-1158 Chemical Properties |
| Boiling point | 574.1±60.0 °C(Predicted) | | density | 1.299±0.06 g/cm3(Predicted) | | pka | 2.13±0.40(Predicted) |
| | CB-1158 Usage And Synthesis |
| Uses | (3R,4S)-3-Amino-1-[(2S)-2-amino-1-oxopropyl]-4-(3-boronopropyl)-3-pyrrolidinecarboxylic Acid Dihydrochloride is a salt analog of (3R,4S)-3-Amino-1-[(2S)-2-amino-1-oxopropyl]-4-(3-boronopropyl)-3-pyrrolidinecarboxylic Acid (CAS# 2095732-06-0), which inhibits arginase 1 (Arg1) enzyme and blocks myeloid cell-??mediated immune suppression in the tumor microenvironment. |
| | CB-1158 Preparation Products And Raw materials |
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