2,2'-Biquinoline-4,4-dicarboxylic acid disodium salt

2,2'-Biquinoline-4,4-dicarboxylic acid disodium salt Basic information
Product Name:2,2'-Biquinoline-4,4-dicarboxylic acid disodium salt
Synonyms:SodiumBicinchoninate;BCA DISODIUM SALT;BCA;BICINCHONINIC ACID DISODIUM SALT;BICINCHONINIC ACID DISODIUM SALT HYDRATE;DI-SODIUM 2,2'-BICINCHONINATE;DISODIUM 2,2'-BIQUINOLINE-4,4'-DICARBOXYLATE;2,2'-BICINCHONINIC ACID DISODIUM SALT
CAS:979-88-4
MF:C20H13N2NaO4
MW:368.32
EINECS:629-761-2
Product Categories:marker
Mol File:979-88-4.mol
2,2'-Biquinoline-4,4-dicarboxylic acid disodium salt Structure
2,2'-Biquinoline-4,4-dicarboxylic acid disodium salt Chemical Properties
Melting point 300℃
storage temp. Inert atmosphere,2-8°C
solubility 0.5% sodium bicarbonate: soluble50mg/mL
form Powder/Chunks
color white to light yellow
Water Solubility Soluble in water.
Stability:Hygrscopic
InChIKeyAUPXFICLXPLHBB-UHFFFAOYSA-L
CAS DataBase Reference979-88-4(CAS DataBase Reference)
EPA Substance Registry System[2,2'-Biquinoline]-4,4'-dicarboxylic acid, disodium salt (979-88-4)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 36/37-42-36/38-36/37/38-20/21/22
Safety Statements 22-26-36/37-45-36
WGK Germany 3
TSCA Yes
HS Code 29339900
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
2,2'-Biquinoline-4,4-dicarboxylic acid disodium salt Usage And Synthesis
Description2,2’-Biquinoline-4,4’-dicarboxylic acid (BCA) is a colorimetric reagent for the detection of copper (Cu+). BCA and Cu+ form a stable 2:1 complex that has an absorbance maximum at 562 nm. It is commonly used as a reagent in the colorimetric BCA protein quantitation assay in which Cu2+ is converted to Cu+ as a function of protein concentration under alkaline conditions.
Chemical PropertiesWhite to light yellow powder
UsesFor determination of Cu and protein assays.Bicinchoninic acid disodium salt is useful for the determination of copper. It is also used for the determination of protein concentration.
Uses
  • Bicinchoninic acid disodium salt hydrate has been used to monitor the levels of reducing sugars, thereby helping in the detection of chitinases.
  • It has also been used to determine the amount of cellulose reducing ends (micromoles/g cellulose).
  • It has been used for determining protein concentration.
Application2,2'-Bicinchoninic Acid Disodium Salt is a photometric reagent for protein assay. It is used for determination of reducing sugar and protein via Cu(I). Also a specific reagent for Cu(I) with sensitivity similar to that of neocuproin.
Biochem/physiol ActionsBicinchoninic acid is used for the determination of protein concentration. It is responsible for the making of intense purple complex with cuprous ion (Cu+), in presence of alkaline conditions. The amount of Cu+ is in relation with the protein concentration.
2,2'-Biquinoline-4,4-dicarboxylic acid disodium salt Preparation Products And Raw materials
Potassium hydrogen phthalate 1,3-Acetonedicarboxylic acid Ethyl 2-(Chlorosulfonyl)acetate Dicarboxylic Acid Isophthalic acid BCA,BCA REAGENT A, 250 ML POLY(ETHYLENE GLYCOL) BIS(CARBOXYMETHYL) ETHER Folic acid Glycine 2,5-PYRIDINEDICARBOXYLIC ACID Phthalic acid 2,2'-Biquinoline-4,4-dicarboxylic acid disodium salt phosphoric acid Ethylenediaminetetraacetic acid disodium salt Sodium 3-nitrobenzoate Bis(2-ethylhexyl) phthalate Calconcarboxylic acid Dimethyl phthalate

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