|
| | (3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one Basic information |
| Product Name: | (3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one | | Synonyms: | Ezetimibe impuriry 11/
4”DeFluoro-4”methyl-Ezetimibe/(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one;(3R,4S)-1-(4-fluorophenyl);Ezetimibe-9;(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one;4-Desfluoro-4-methyl Ezetimibe;4”DeFluoro-4”methyl-Ezetimibe;2-Azetidinone, 1-(4-fluorophenyl)-3-[(3S)-3-hydroxy-3-(4-methylphenyl)propyl]-4-(4-hydroxyphenyl)-, (3R,4S)-;3?-(4-Methylphenyl)ezetimibe | | CAS: | 1700622-07-6 | | MF: | C25H24FNO3 | | MW: | 405.46 | | EINECS: | | | Product Categories: | | | Mol File: | 1700622-07-6.mol |  |
| | (3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one Chemical Properties |
| Melting point | 161-164°C | | Boiling point | 663.6±55.0 °C(Predicted) | | density | 1.271±0.06 g/cm3(Predicted) | | storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 9.72±0.30(Predicted) | | color | Off-White to Pale Beige | | Stability: | Hygroscopic |
| | (3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one Usage And Synthesis |
| Uses | 4”DeFluoro-4”methyl-ezetimibe is a derivative of Ezetimibe (E975000), which is an antihyperlipoproteinemic and a cholesterol absorption inhibitor. |
| | (3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one Preparation Products And Raw materials |
|
