ACT 373898

ACT 373898 Basic information
Product Name:ACT 373898
Synonyms:ACT 373898;Macitentan Impurity 7;Macitentan ACT-373898;Acetic acid, 2-[[5-(4-bromophenyl)-6-[[(propylamino)sulfonyl]amino]-4-pyrimidinyl]oxy]-;Macitentan ACT-373898Q: What is Macitentan ACT-373898 Q: What is the CAS Number of Macitentan ACT-373898 Q: What is the storage condition of Macitentan ACT-373898 Q: What are the applications of Macitentan ACT-373898;2-((5-(4-bromophenyl)-6-((N-propylsulfamoyl)amino)pyrimidin-4-yl)oxy)acetic acid;Macitentan?Impurity?9/2-[[5-(4-Bromophenyl)-6-[[(propylamino)sulfonyl]amino]-4-pyrimidinyl]oxy]-acetic?acid;Macitentan?Impurity?9/2-[[5-(4-Bromophenyl)-6-[[(propylamino)sulfonyl]amino]-4-pyrimidinyl]oxy]-acetic?acid 1433875-14-9
CAS:1433875-14-9
MF:C15H17BrN4O5S
MW:445.29
EINECS:
Product Categories:
Mol File:1433875-14-9.mol
ACT 373898 Structure
ACT 373898 Chemical Properties
Boiling point 596.6±60.0 °C(Predicted)
density 1.620±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO: soluble,Ethanol: soluble
form A solid
pka1.59±0.10(Predicted)
Stability:Hygroscopic
Safety Information
MSDS Information
ACT 373898 Usage And Synthesis
UsesACT 373898 Disodium Salt is an impurity of Macitentan (M105005), an orally active endothelin receptor antagonist used for pulmonary arterial hypertension.
ACT 373898 Preparation Products And Raw materials
Macitentan Impurity 17 CarbaMic acid, N-[(propylaMino)sulfonyl]-, phenylMethyl ester Macitentan Impurity 13 ACT 080803 Macitentan Impurity 2 Macitentan Impurity 4 Macitentan Impurity 14 Macitentan impurity A Macitentan Impurity 3 Macitentan Impurity 10 N-DesMethyl Maprotiline HCl Salt Macitentan Impurity 11 Macitentan Impurity 15 Macitentan impurity B Macitentan Impurity 12 Maprotiline EP Impurity B SulfaMide, N-[5-(4-broMophenyl)-6-chloro-4-pyriMidinyl]-N'-propyl- N-Methyl Maprotiline

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