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Sitagliptin EP Impurity B

Sitagliptin EP Impurity B Basic information
Product Name:Sitagliptin EP Impurity B
Synonyms:Sitagliptin EP Impurity B;Sitagliptin impurity 3/Sitagliptin EP Impurity B/Sitagliptin 4-Desfluoro Impurity/(R)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,5-difluorophenyl)butan-2-amine phosphate;4-Desfluoro Sitagliptin;(R)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,5-difluorophenyl)butan-2-amine phosphate;4-Desfluoro Sitagliptin Phosphate;Sitagliptin EP Impurity B Phosphate;Sitagliptin EP Impurity B / Sitagliptin 4-Desfluoro Impurity;Sitagliptin?4-Desfluoro?Impurity
CAS:1345822-87-8
MF:C16H19F5N5O5P
MW:487.318337
EINECS:
Product Categories:
Mol File:1345822-87-8.mol
Sitagliptin EP Impurity B Structure
Sitagliptin EP Impurity B Chemical Properties
Safety Information
MSDS Information
Sitagliptin EP Impurity B Usage And Synthesis
Uses4-Desfluoro Sitagliptin is a metabolite of Sitagliptin phosphate (S491000). Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.
Sitagliptin EP Impurity B Preparation Products And Raw materials
Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate Sitagliptin Sitagliptin Impurity 34 2-(3-(methylamino)-1-(thiophen-2-yl)propyl)naphthalen-1-ol (RS)-1-[3-(MethylaMino)-1-(2-thienyl)propyl]-2-naphthalenol (S)-Sitagliptin Phosphate (R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione Benzenebutanoicacid,b-aMino-2,4,5-trifluoro-,Methylester,(bR)- Sitagliptin Impurity 35 Sitagliptin N-Boc IMpurity Methyl 3-acetamido-4-(2,4,5-trifluorophenyl)but-2-enoate rac-Sitagliptin 1,2,4-Triazolo[4,3-a]pyrazine, 7-[3-amino-1-oxo-4-(2,4,5-trifluorophenyl)-2-butenyl]-5,6,7,8-tetrahydro- 3-(trifluoromethyl)- BOC-(S)-3-AMINO-4-(2,4,5-TRIFLUORO-PHENYL)-BUTYRIC ACID Sitagliptin N-Sulfate 7-[(3R)-3-[(N-Acetyl)AMino]-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoroMethyl)-1,2,4-triazolo[4,3-a]pyrazine rac-Sitagliptin EP Impurity B HCl 2,4,5-Trifluorobenzaldehyde
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