Isomannide

Isomannide Basic information
Product Name:Isomannide
Synonyms:1,4:3,6-DIANHYDROMANNITOL;ISOMANNIDE;1,4;Perhydro-3,6-dihydroxyfuro[3,2-b]furan;Keratin 5 &;Milnacipran Impurity 14;(3R,3aR,6R,6aR)-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3,6-diol;I**isomannide、1,4:3,6-dianhydro-D-manni
CAS:641-74-7
MF:C6H10O4
MW:146.14
EINECS:211-374-1
Product Categories:Alcohols and Derivatives;Heterocycles;Glycon Biochem
Mol File:641-74-7.mol
Isomannide Structure
Isomannide Chemical Properties
Melting point 80-85 °C (lit.)
alpha 89 º (c=3, H2O)
Boiling point 150 °C / 12mmHg
density 1.0945 (rough estimate)
refractive index 1.4128 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly), Water
form Solid
pka13.17±0.40(Predicted)
color White to Off-White
optical activity[α]25/D +89°, c = 3 in H2O
Water Solubility almost transparency
BRN 80509
CAS DataBase Reference641-74-7(CAS DataBase Reference)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
10-21
HS Code 29329990
MSDS Information
ProviderLanguage
Isomannide English
SigmaAldrich English
ALFA English
Isomannide Usage And Synthesis
Chemical PropertiesWhite to off-white powder
Uses1,4:3,6-Dianhydro-D-mannitol is a reagent used in the synthesis of new isomannide-based peptidomimetic as human tissue kallikrein 1 inhibitor using Ugi multicomponent reaction. It also functions as a chiral ligand for stereoselective synthesis.
Isomannide Preparation Products And Raw materials
Raw materialsSorbitol-->Isosorbide dimethyl ether-->Dimethyl carbonate
D-Mannose Isomannide dinitrate ISOMANNIDE = 1,4:3,6-DIANHYDROMANNITOL,ISOMANNIDE = 1,4:3,6-DIANHYDROMANNITOL Mannitol Isomannide mononitrate Isomannide dianhydromannitol D-Mannitol Dianhydromannitol monooleate

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