Terazosin IMpurity J

Terazosin IMpurity J Basic information
Product Name:Terazosin IMpurity J
Synonyms:Terazosin IMpurity J;1-[4-(4-AMino-6,7-diMethoxy-2-quinazolinyl)-1-piperazinyl]-2-hydroxy-1-pentanone;Terazosin Impurity 10(Terazosin EP Impurity J);Terazosin EP IMP J;1-[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-2-hydroxypentan-1-one;1-Pentanone, 1-[4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-hydroxy-;Terazosin Hydrochloride Dihydrate - Impurity J;1-(4-(4-Amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)-2-hydroxypentan-1-one (Terazosin Impurity)
CAS:152551-75-2
MF:C19H27N5O4
MW:389.45
EINECS:
Product Categories:Aromatics, Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:152551-75-2.mol
Terazosin IMpurity J Structure
Terazosin IMpurity J Chemical Properties
Melting point 204-206°C
Boiling point 652.9±65.0 °C(Predicted)
density 1.288±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, Refrigerator, under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly, Heated)
pka13.90±0.20(Predicted)
form Solid
color White to Pale Yellow
Stability:Hygroscopic
Safety Information
MSDS Information
Terazosin IMpurity J Usage And Synthesis
Uses1-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-hydroxy-1-pentanone is an impurity of Terazosin (T105000), an α-1-adrenergic blocker that is related to Prazosin (P702325).
Terazosin IMpurity J Preparation Products And Raw materials
Terazosin impurity 2-Piperazine-4-amino-6,7-dimethoxyquinazoline (R)-Terazosin 2,2'-(1,4-Piperazinediyl)bis[6,7-diMethoxy-4-quinazolinaMine] 1-[4-(4-AMino-6,7-diMethoxy-2-quinazolinyl)-1-piperazinyl]-5-hydroxy-1-pentanone 6,7-DiMethoxy-2-(4-(tetrahydrofuran-2-carbonyl)piperazin-1-yl)quinazolin-4(1H)-one Terazosin EP IMpurity D [4-(4-AMino-7-hydroxy-6-Methoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)Methanone NSC 351869 1-(2-Furoyl)piperazine [4-(4-AMino-6,7-diMethoxy-2-quinazolinyl)-1-piperazinyl][(5S)-tetrahydro-5-Methyl-2-furanyl]Methanone Terazosin hydrochloride dihydrate Piperazine, 1-[[(2R)-tetrahydro-2-furanyl]carbonyl]- (9CI) Prazosin hydrochloride [4-(4-AMino-6-hydroxy-7-Methoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)Methanone Terazosin EP Impurity O 1-(Tetrahydro-2-furoyl)piperazine Terazosin hydrochloride

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