ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards (4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate

(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate

(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate Basic information
Product Name:(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate
Synonyms:(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate;tert-Butyl 2-((4R,6S)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate;Atorvastatin Acetonide t-Butyl Ester Side Chain (4R,6S)-Isomer;Atorvastatin Impurity 61;Atorvastatin A8 intermediate 4R6S Diastereomer;Atorvastatin Impurity Z;(4R,6S)-1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester;1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6S)-
CAS:196085-84-4
MF:C14H23NO4
MW:269.34
EINECS:
Product Categories:
Mol File:196085-84-4.mol
(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate Structure
(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate Chemical Properties
Boiling point 364.1±17.0 °C(Predicted)
density 1.016±0.06 g/cm3(Predicted)
storage temp. 2-8°C
Safety Information
MSDS Information
(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate Usage And Synthesis
Uses(4R,6S)-6-(Cyanomethyl)-2,2-dimethyl--1,3-dioxane-4-acetic Acid tert-Butyl Ester is an impurity in the synthesis of Atorvastatin (A791750), a selective, competitive HMG-CoA reductase . Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.
(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate Preparation Products And Raw materials
Ortho-Hydroxy atorvastatin calcium salt O-Methyl Atorvastatin Calcium Salt Atorvastatin IMpurity G Atorvastatin Impurity 20 2,3-Dehydroxy Atorvastatin Sodium Salt Atorvastatin Impurity 15 3-Oxo Atorvastatin tert-Butyl Ester Atorvastatin ATV-FX1 sodiuM salt di(2-Hydroxy Atorvastatin) CalciuM Salt P-HYDROXY ATORVASTATIN LACTONE Atorvastatin Oxirane Impurity 3S,5R isoMer, or (3S,5R)-7-[3-(phenylcarbaMoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calciuM salt Atorvastatin Dehydro Lactone 2-[1,2-Bis-(4-fluoro-phenyl)-2-oxo-ethyl]-4-methyl-3-oxo-pentanoic acid phenylamide Difluoro Atorvastatin Acetonide tert-Butyl Ester Atorvastatin Impurity 31 Atorvastatin Impurity 38
Email:[email protected] [email protected]
Copyright © 2024 Mywellwork.com All rights reserved.