5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine

5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine Basic information
Product Name:5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine
Synonyms:N4-Benzoyl-5'-O-(4,4'-diMethoxytrityl)-2'-deoxycytidine;N-[1-[5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-4-hydroxy-oxolan-2-yl]-2-oxo-pyrimidin-4-yl]benzamide;5'-O-DIMETHOXYTRITYL-N-BENZOYL-DESOXYCYTI-DINE, 98+%;5'-O-(4,4'-Dimethoxytrityl)-N-benzoyl-2'-deoxycytidine;N-[1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-β-D-ribofuranosyl]-2-oxo-1,2-dihydropyrimidine-4-yl]benzamide;N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxycytidine;N-Benzoyl-5'-O-(4,4'-diMethoxytrityl)-2'-deoxycytidine;N4-Bz-DMT-dC
CAS:67219-55-0
MF:C37H35N3O7
MW:633.69
EINECS:266-605-9
Product Categories:Biochemicals and Reagents;Building Blocks;C12 to C30+;Chemical Synthesis;Heterocyclic Building Blocks;Nucleoside Analogs;Biochemistry;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Nucleic acids;Nucleosides;Nucleotides;Oligonucleotides;Pyrimidines;Organics;PNS
Mol File:67219-55-0.mol
5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine Structure
5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine Chemical Properties
Melting point 119 °C
Boiling point 668.71°C (rough estimate)
density 1.2234 (rough estimate)
refractive index 58 ° (C=1, MeOH)
storage temp. 2-8°C
solubility DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml
form powder to crystaline
pka8.67±0.20(Predicted)
color White to Almost white
Water Solubility 100μg/L at 20℃
BRN 601627
LogP5.3 at 20℃
CAS DataBase Reference67219-55-0(CAS DataBase Reference)
EPA Substance Registry SystemCytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy- (67219-55-0)
Safety Information
Hazard Codes Xn,Xi,T
Risk Statements 40-36/37/38-20/21/22-46-45
Safety Statements 36/37-36-26-22-45-53
RIDADR UN 3077 9 / PGIII
WGK Germany 1
1-3-10
HS Code 29349990
MSDS Information
ProviderLanguage
5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine English
SigmaAldrich English
ACROS English
5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine Usage And Synthesis
Chemical PropertiesOff-white powder
Uses5''-O-(4,4''-Dimethoxytrityl)-N4-benzoyl-2''-deoxycytidine (CAS# 67219-55-0) is a cytidine nucleoside derivative, and has been used as a reactant with synthetic modified DNA and RNA, such as in the site-selective RNA activation by acridine-modified oligodeoxynucleotides in metal-ion catalyzed hydrolysis.
UsesN4-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxycytidine has been used as research tool for anti-viral and anti-cancer studies.
General DescriptionThe 3′-O-(2-cyanoethyl)-N,N-diisopropylphosphoramidite derivatives of N4-benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxycytidine (DMT-dCBz) participates in Diels-Alder reaction between diene-modified oligonucleotides and maleimide-derivatized peptides.
Flammability and ExplosibilityNotclassified
5'-O-FDMT-N4-BENZOYL-2'-DEOXYCYTIDINE CEP 5'DIMETHOXYTRITYL DA(BZ)+DG(IBU)+DC(BZ)+T BETA-CYANOETHYL PHOSPHORAMIDITE Benzoyl peroxide Cytidine-5'-triphosphate disodium salt dihydrate 5'-O-(4,4'-DIMETHOXYTRITYL)-N4-BENZOYL-2'-DEOXYCYTIDINE-3'-LCAA-CPG 5'-O-(4,4'-DIMETHOXYTRITYL)-N4-BENZOYL-5-METHYL-2'-DEOXYCYTIDINE 5-Azacytidine Sodium lauroylglutamate 5'-DIMETHOXYTRITYL-N4-BENZOYL-2'-DEOXYCYTIDINE-3'-(METHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE N-blocked-5'-O-DMT-2'-O-TBDMS CED cytidine phosphoramidite 5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine 5'DIMETHOXYTRITYL DC(BZ)+T BETA-CYANOETHYL PHOSPHORAMIDITE 1,1-Dimethoxyethane 5'-O-(4,4'-DIMETHOXYTRITYL)-N4-BENZOYL-2'-DEOXYCYTIDINE-3'-O-SUCCINIC ACID N-blocked-5'-O-DMT-2'-O-Me CED cytosine phosphoramidite DMT-C(N-BZ) 2'OME 5'-O-DMT-N4-Benzoyl-2'-deoxycytidine 3'-CE phosphoramidite N4-BENZOYL-5'-O-(DIMETHOXYTRITYL)-5-METHYL-2'-O-METHYLCYTIDINE

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