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Azelastine N-Oxide

Azelastine N-Oxide Basic information
Product Name:Azelastine N-Oxide
Synonyms:Azelastine N-Oxide (Mixture of DiastereoMers);4-[(4-Chlorophenyl)Methyl]-2-(hexahydro-1-Methyl-1-oxido-1H-azepin-4-yl)-1(2H)-phthalazinone;(R)-4-[(4-Chlorophenyl)Methyl]-2-(hexahydro-1-Methyl-1-oxido-1H-azepin-4-yl)-1(2H)-phthalazinone;(S)-4-[(4-Chlorophenyl)Methyl]-2-(hexahydro-1-Methyl-1-oxido-1H-azepin-4-yl)-1(2H)-phthalazinone;Azelastine N-Oxide;4-[(4-chlorophenyl)methyl]-2-(1-methyl-1-oxidoazepan-1-ium-4-yl)phthalazin-1-one;1(2H)-Phthalazinone, 4-[(4-chlorophenyl)methyl]-2-(hexahydro-1-methyl-1-oxido-1H-azepin-4-yl)-;Azdrostine N-oxide (diastereoisomer mixture)
CAS:640279-88-5
MF:C22H24ClN3O2
MW:397.9
EINECS:
Product Categories:Aromatics;Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
Mol File:640279-88-5.mol
Azelastine N-Oxide Structure
Azelastine N-Oxide Chemical Properties
Melting point >130°C (dec.)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka4.97±0.40(Predicted)
form Solid
color White to Yellow
Stability:Hygroscopic
Safety Information
HS Code 2933998350
MSDS Information
Azelastine N-Oxide Usage And Synthesis
Chemical PropertiesPale Yellow Solid
UsesA metabolite of Azelastine (A808250).
Azelastine N-Oxide Preparation Products And Raw materials
4-(4-Chloro-benzyl)-2H-phthalazin-1-one Azelastine Hydrochloride IMpurity D N'-(1-Methylazepan-4-yl)benzohydrazine 4-(4-CHLOROBENZYL)-2-(2-(1-METHYLPYRROLIDIN-2-YL)ETHYL)PHTHALAZIN-1(2H)-ONE Benzoic acid, 2-(hexahydro-1-Methyl-1H-azepin-4-yl)hydrazide 2-((4-Chlorophenyl)acetyl)benzoic acid 4-[(3-Chlorophenyl)Methyl]-2-(hexahydro-1-Methyl-1H-azepin-4-yl)-1(2H)-phthalazinone Azelastine-d4 HCl (S)-Azelastine N-Oxide (Mixture of DiastereoMers) azelastine hydrochloride Azelastine Impurity 1 HCl Benzoyl hydrazine N-DesMethyl Azelastine-d4 Azelastine Impurity 2 HCl Azelastine-13C,d3 (R)-Azelastine N-Oxide (Mixture of DiastereoMers) Azelastine Impurity AS-03 azelastine hydrochloride
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