ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards rac a-Hydroxy Ibuprofen

rac a-Hydroxy Ibuprofen

rac a-Hydroxy Ibuprofen Basic information
Product Name:rac a-Hydroxy Ibuprofen
Synonyms:α-Ηydroxy-α-Methyl-4-(2-Methylpropyl)benzeneacetic Acid;rac a-Hydroxy Ibuprofen;2-hydroxy-2-(4-isobutylphenyl)propanoic acid;IBuprofen Impurity 13;Ibuprofen EP Impurity M;Imp. M (EP): (2RS)-2-Hydroxy-2-[4-(2-methylpropyl)phenyl]propanoic Acid;rac α-Hydroxy Ibuprofen(Ibuprofen EP Impurity M);Ibuprofen impurity 7/Ibuprofen EP Impurity M/rac a-Hydroxy Ibuprofen/2-hydroxy-2-(4-isobutylphenyl)propanoic acid
CAS:60057-62-7
MF:C13H18O3
MW:222.28
EINECS:
Product Categories:Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:60057-62-7.mol
rac a-Hydroxy Ibuprofen Structure
rac a-Hydroxy Ibuprofen Chemical Properties
Melting point 95-97°C
Boiling point 367.9±27.0 °C(Predicted)
density 1.122±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form Solid
pka3.62±0.25(Predicted)
color White to Off-White
Safety Information
MSDS Information
rac a-Hydroxy Ibuprofen Usage And Synthesis
Chemical PropertiesOff-White Solid
UsesA potential precursor of Ibuprofen and Naproxen. Antiinflammatory agent.
Synthesis Reference(s)The Journal of Organic Chemistry, 60, p. 742, 1995 DOI: 10.1021/jo00108a047
rac a-Hydroxy Ibuprofen Preparation Products And Raw materials
Preparation Products1-Hydroxyibuprofen-->4'-(2-Methylpropyl)acetophenone
(S)-(+)-Ibuprofen (2RS)-2-(4-ISOBUTYRYLPHENYL)PROPANOIC ACID Ibuprofen Ethyl Ester 2-[4-(2-Methylpropyl)phenyl] ethanol 6-isobutyl-3-methyl-2,3-dihydro-1H-inden-1-one 2-(4-Methylphenyl)propanoic acid 4'-(2-Methylpropyl)acetophenone 2-[4-(2-HYDROXY-2-METHYLPROPYL)PHENYL]PROPIONIC ACID 4-(2-Methylpropyl)benzeneethanol (R)-(-)-IBUPROFEN Ibuprofen (2RS)-2-[4-(2-METHYLPROPYL)PHENYL]PROPANAMIDE (2RS)-2-(4-FORMYLPHENYL)PROPANOIC ACID (2RS)-2-(4-ISOBUTYLPHENYL)PROPAN-1-OL 2-[4-(1-METHYLPROPYL)PHENYL]PROPANOIC ACID (2RS)-2-(4-ETHYLPHENYL)PROPANOIC ACID trans-Ibuprofen IMpurity G M-ISOBUTYL IBUPROFEN
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