3-Hydroxy-6-methylpyridine

3-Hydroxy-6-methylpyridine Basic information

Product Name:	3-Hydroxy-6-methylpyridine
Synonyms:	6-methyl-3-pyridino;2-METHYL-5-HYDROXY PYRIDINE;5-HYDROXY-2-PICOLINE;5-HYDROXY-2-METHYLPYRIDINE;6-METHYLPYRIDIN-3-OL;6-METHYL-3-HYDROXYPYRIDINE;6-METHYL-3-PYRIDINOL;3-HYDROXY-6-METHYLPYRIDINE
CAS:	1121-78-4
MF:	C6H7NO
MW:	109.13
EINECS:	214-337-8
Product Categories:	Heterocycle-Pyridine series;Pyridine;Pyridine Series;Pyridines, Pyrimidines, Purines and Pteredines;Heterocycles
Mol File:	1121-78-4.mol

3-Hydroxy-6-methylpyridine Chemical Properties

Melting point	168-170 °C(lit.)
Boiling point	204.59°C (rough estimate)
density	1.1143 (rough estimate)
refractive index	1.5040 (estimate)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	dichloromethane: soluble
pka	9.49±0.10(Predicted)
form	Crystalline Powder
color	Beige to light tan
BRN	107077
InChIKey	DHLUJPLHLZJUBW-UHFFFAOYSA-N
LogP	0.418 (est)
CAS DataBase Reference	1121-78-4(CAS DataBase Reference)
NIST Chemistry Reference	3-Pyridinol, 6-methyl-(1121-78-4)

Safety Information

Hazard Codes	Xn,Xi
Risk Statements	22-37/38-41-40-36/37/38
Safety Statements	26-39-24/25-36-22
WGK Germany	3
RTECS	UU7714900
HS Code	29333990
Toxicity	mouse,LD50,intraperitoneal,846mg/kg (846mg/kg),Toxicon. Vol. 23, Pg. 815, 1985.

MSDS Information

3-Hydroxy-6-methylpyridine Usage And Synthesis

Chemical Properties

beige to light tan crystalline powder

Uses

5-Hydroxy-2-methylpyridine was used as starting reagent for the synthesis of 5-[(4-methoxybenzyl)oxy]-2-pyridinecarbaldehyde.
It was used in synthesis of [HNC₆H₆OH]₂[Cu(NC₅H₅)₄(NbOF₅)₂].
It was used as ligand of a platinum complex which showed protein kinase inhibitory action at nanomolar levels.
It forms a chiral pyridinium ionic liquid on reaction with L-menthol chloromethyl ether.

3-Hydroxy-6-methylpyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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