D(-)-Glutamic acid

D(-)-Glutamic acid Basic information
Product Name:D(-)-Glutamic acid
Synonyms:(2R)-2-Aminoglutaric acid;D-α-AMinoglutaric acid;D-1-AMinopropane-1,3-dicarboxylic acid;D(-)-GlutaMic acid, 99+% 25GR;D(-)-GlutaMic acid, 99+% 5GR;(2R)-GlutaMic Acid;NSC 77686;D-Glutaminic acid
CAS:6893-26-1
MF:C5H9NO4
MW:147.13
EINECS:230-000-8
Product Categories:amino acid;Glutamate receptor;Amino ACIDS SERIES;Glutamic acid [Glu, E];Amino Acids and Derivatives;alpha-Amino Acids;Amino Acids;Biochemistry;for Resolution of Bases;Optical Resolution;Synthetic Organic Chemistry;Nutritional Supplements;Amino Acids
Mol File:6893-26-1.mol
D(-)-Glutamic acid Structure
D(-)-Glutamic acid Chemical Properties
Melting point 200-202 °C (subl.)(lit.)
alpha -31.3 º (c=10, 2 N HCl)
Boiling point 267.21°C (rough estimate)
density 1.5380
refractive index 1.4210 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Water (Slightly)
pkapK1:2.162(+1);pK2:4.272(0);pK3:9.358(-1) (25°C)
form Powder
color White to off-white
Water Solubility 7 g/L (20 ºC)
Merck 14,4469
BRN 1723800
InChIKeyWHUUTDBJXJRKMK-GSVOUGTGSA-N
LogP-0.969 (est)
CAS DataBase Reference6893-26-1(CAS DataBase Reference)
NIST Chemistry ReferenceD-Glutamic acid(6893-26-1)
EPA Substance Registry SystemD-Glutamic acid (6893-26-1)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 24/25-36-26
WGK Germany 3
10
TSCA Yes
HS Code 29224200
MSDS Information
ProviderLanguage
D-2-Aminoglutaric acid English
ACROS English
SigmaAldrich English
ALFA English
D(-)-Glutamic acid Usage And Synthesis
Chemical PropertiesWhite cryst. powder
UsesD-Glutamic Acid is the unnatural (R)-enantiomer of Glutamic Acid, a non-essential amino acid. Its salt form (glutamate) is an important neurotransmitter that plays a key role in long-term potentiation and is important for learning and memory. Glutamic Acid is also a key molecule in cellular metabolism.
UsesD-Glutamic acid acts as a superior to alpha ketoglutarate. It helps in the growth of Lactobacillus arabinosus. It can inhibit the IgE binding to peanut allergens. It is widely used in pharmaceuticals and foods.
UsesD-glutamic acid is suitable for use in the structure-affinity relationship (SAR)-study of GR (glutamate racemase) enzyme and its inhibitors.
DefinitionChEBI: An optically active form of glutamic acid having D-configuration.
General DescriptionD-Glutamic acid is an essential constituent of the bacterial peptidoglycan structure. It is added to UDP-N-acetylmuramyl-L-alanine (UDP-MurNAc-L-alanine) by the enzyme D-glutamic acid-adding enzyme (murD). This is, then, incorporated into the peptidoglycan precursor. Peptidoglycan makes up the cell walls of Gram-positive and -negative bacteria. The conversion of L-glutamate to D-glutamate by glutamate racemase (GR) enzyme is an essential step in the synthesis of peptidoglycan.
Biological ActivityExcitatory amino acid acting at NMDA receptors; less active than the L-isomer.
Biochem/physiol ActionsUnnatural isomer of glutamic acid.
storageRoom temperature
Boc-L-Glutamic acid 1-benzyl ester BOC-D-GLU-OME Z-D-GLU-OH BOC-D-GLU-OTBU H-D-GLU(OBZL)-OH Z-D-GLA(OTBU)2-OH Polyglutamic acid D-CYSTEINE HYDROCHLORIDE MONOHYDRATE Boc-D-Glu-OBzl L-Glutamic acid Z-D-GLU(OBZL)-OH D(-)-Glutamic acid D(-)-AMETHOPTERIN HYDRATE, 98 BOC-D-GLU(OTBU)-OH L-(+)-Glutamic acid hydrochloride phosphoric acid (R)-(-)-N-(P-TOLYLSULPHONYL)GLUTAMIC ACID LABOTEST-BB LT00455703

Email:[email protected] [email protected]
Copyright © 2024 Mywellwork.com All rights reserved.