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| | 2-Butynoic acid Basic information |
| | 2-Butynoic acid Chemical Properties |
| Melting point | 78-80 °C (lit.) | | Boiling point | 200-203°C | | density | 0,9641 g/cm3 | | refractive index | 1.3918 (estimate) | | Fp | 200-203°C | | storage temp. | Sealed in dry,2-8°C | | solubility | water: soluble50mg/mL, clear to very slightly hazy, colorless to very faintly yellow | | pka | 2.62(at 25℃) | | form | Powder | | color | White to yellow | | Water Solubility | Soluble in water. Slightly soluble in methanol and chloroform. | | BRN | 1740205 | | InChIKey | LUEHNHVFDCZTGL-UHFFFAOYSA-N | | CAS DataBase Reference | 590-93-2(CAS DataBase Reference) | | NIST Chemistry Reference | 2-Butynoic acid(590-93-2) | | EPA Substance Registry System | 2-Butynoic acid (590-93-2) |
| Hazard Codes | C | | Risk Statements | 34-20/21/22 | | Safety Statements | 26-27-36/37/39-45 | | RIDADR | UN 3261 8/PG 2 | | WGK Germany | 3 | | TSCA | Yes | | HazardClass | 8 | | PackingGroup | II | | HS Code | 29161900 |
| | 2-Butynoic acid Usage And Synthesis |
| Chemical Properties | white to yellow powder | | Uses | Synthon employed in a variety of reactions, including cycloacylation of phenols to flavones and chromones,1 and cyclization to γ-butyrolactones.2 | | Uses | 2-Butynoic acid is used as an intermediate in organic synthesis and pharmaceuticals. It is used as a synthon in various reactions, which includes cylcoalkylation of phenols to flavones and chromones. It is involved in the cyclization of gamma-butyrolactones. It is also used in the synthesis of Z-trisubstituted olefins through μ-alkylation. It plays an important role in the preparation of chirally pure 1,2,3,4-tetrahydroisoquinoline analogs, which finds application as anti-cancer agents. | | General Description | The rotational spectrum of 2-butynoic acid was measured by pulsed supersonic-jet Fourier transform microwave spectroscopy. |
| | 2-Butynoic acid Preparation Products And Raw materials |
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