5,6-Diamino-1,3-dimethyluracil hydrate

5,6-Diamino-1,3-dimethyluracil hydrate Basic information
Product Name:5,6-Diamino-1,3-dimethyluracil hydrate
Synonyms:2,4(1H,3H)-Pyrimidinedione, 5,6-diamino-1,3-dimethyl-;5,6-DiaMino-1,3-diMethyluracil hydrate technical grade;5,6-Diamino-1,3-dimethylurea;2,4(1H,3H);5,6-DIAMINO-1,3-DIMETHYLURACIL HYDRATE;3h)-pyrimidinedione,5,6-diamino-1,3-dimethyl-4(1h;5,6-Diamino-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione;Uracil, 5,6-diamino-1,3-dimethyl-
CAS:5440-00-6
MF:C6H10N4O2
MW:170.17
EINECS:226-621-9
Product Categories:Nucleotides and Nucleosides;5-FOA;Bases & Related Reagents;Nucleotides;Building Blocks;C6 to C8;Chemical Synthesis;Heterocyclic Building Blocks;Pyrimidines
Mol File:5440-00-6.mol
5,6-Diamino-1,3-dimethyluracil hydrate Structure
5,6-Diamino-1,3-dimethyluracil hydrate Chemical Properties
Melting point 210-214 °C (dec.)(lit.)
Boiling point 243.6±50.0℃ (760 Torr)
density 1.350±0.06 g/cm3 (20 ºC 760 Torr)
Fp 101.1±30.1℃
solubility DMSO, Methanol
pka4.42±0.70(Predicted)
form Solid
color Pale Brown
BRN 157451
EPA Substance Registry System2,4(1H,3H)-Pyrimidinedione, 5,6-diamino-1,3-dimethyl- (5440-00-6)
Safety Information
WGK Germany 3
10-34
MSDS Information
5,6-Diamino-1,3-dimethyluracil hydrate Usage And Synthesis
Chemical PropertiesPale Brown Solid
Uses5,6-Diamino-1,3-dimethyluracil hydrate can be used as reactant involved in the synthesis of biologically active molecules including: 1H-Imidazol-1-yl substituted 8-phenylxanthines for use as adenosine receptor ligands ; Pyrimidinyl purinediones via cyclocondensation ; Theophylline derivatives as adenosine receptor antagonists ; Pteridine analogs for use as monoamine oxidase B and nitric oxide synthase inhibitors ; Fused tricyclic xanthines and Cadmium uraciliminoethylpyridine complexes for use as antiproliferatives against C6 glioma cells6.
Uses5,6-Diamino-1,3-dimethyl Uracil (cas# 5440-00-6) is a compound useful in organic synthesis.
UsesReactant involved in the synthesis of biologically active molecules including:
  • 1H-Imidazol-1-yl substituted 8-phenylxanthines for use as adenosine receptor ligands
  • Pyrimidinyl purinediones via cyclocondensation
  • Theophylline derivatives as adenosine receptor antagonists
  • Pteridine analogs for use as monoamine oxidase B and nitric oxide synthase inhibitors
  • Fused tricyclic xanthines
  • Cadmium uraciliminoethylpyridine complexes for use as antiproliferatives against C6 glioma cells
Purification MethodsIt recrystallises from EtOH. The hydrochloride has m 310o (from MeOH), and the perchlorate has m 246-248o. [UV: Bredereck et al. Chem Ber 92 583 1959, Taylor et al. J Am Chem Soc 77 2243 1955, Beilstein 25 III/IV 4133.]
5,6-Diamino-1,3-dimethyluracil hydrate Preparation Products And Raw materials
Raw materialsCyanoacetic acid
Preparation ProductsISOCAFFEINE-->8-(3-Pyridyl)theophyline-->2,4(1H,3H)-Pteridinedione, 1,3-dimethyl-7-phenyl--->4,6-Dimethyl-1H-1,2,3-triazolo[4,5-d]pyrimidine-5,7(4H,6H)-dione-->NSC14355
1,3-Dimethyluric acid SPECS AB-323/25048306 TOSLAB 154050 TETRAMETHYLURIC ACID ETHYL (6-AMINO-1,2,3,4-TETRAHYDRO-1,3-DIMETHYL-2,4-DIOXO-5-PYRIMIDINYL)-CARBAMATE THEOPHYLLINE (1,3-15N2) 6-AMino-1-isobutyl-3-Methyl-5-nitroso-2,4-pyriMidinedione 5,6-Diamino-1,3-dimethyluracil hydrate 1,3-DIETHYL-5,6-DIAMINOURACIL 1,3-DIMETHYL-5-NITRO-6-[(1,1,1-TRIPHENYL-LAMBDA5-PHOSPHANYLIDENE)AMINO]-1,2,3,4-TETRAHYDROPYRIMIDINE-2,4-DIONE 6-AMINO-1,3-DIMETHYL-5-NITROSOURACIL 6-AMINO-1-BENZYL-3-METHYL-5-(N-FORMYL-N-METHYL)URACIL 1,3,7-TRIMETHYLURIC ACID AKOS BC-1513 [7-CD3]-1,3,7-Trimethyluric Acid 1,3-DIMETHYL-6-AMINO-5-FORMYLAMINOURACIL SPECS AB-323/25048360 N-(6-AMINO-1,3-DIMETHYL-2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL)-2-HYDROXYACETAMIDE

Email:[email protected] [email protected]
Copyright © 2024 Mywellwork.com All rights reserved.