2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene

2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene Basic information

Product Name:	2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene
Synonyms:	Thiophene, 2-(4-fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]-;2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene;2-(4-Fluorophenyl)-5-(5-iodo-2-Methylbenzyl)thiophene;Canagliflozin iMpurity D;2-((5-IODO-2-METHYLPHENYL)METHYL)-5-(4-FLUOROPHENYL)THIOPHENE;Canagliflozin INT5;Canagliflozin Intermediate1;2-(4-Fluorophenyl)
CAS:	898566-17-1
MF:	C18H14FIS
MW:	408.27
EINECS:	618-312-6
Product Categories:	898566-17-1
Mol File:	898566-17-1.mol

2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene Chemical Properties

Melting point	109-110 °C
Boiling point	450.2±45.0 °C(Predicted)
density	1.533
vapor pressure	0-0Pa at 20-25℃
storage temp.	2-8°C(protect from light)
solubility	DMSO (Sparingly), Methanol (Slightly)
form	Solid
color	Pale Yellow
LogP	7.5 at pH7

Safety Information

MSDS Information

2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene Usage And Synthesis

Chemical Properties	Pale Yellow Solid.
Uses	2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene is an antidiabetic agent and a Canagliflozin (C175190) intermediate. Canagliflozin is a sodium/glucose cotransporter 2 (SGLT2) inhibitor and a candidate for the treatment of type 2 diabetes and obesity.

2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene Preparation Products And Raw materials

Raw materials

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