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Brivudine

Brivudine Basic information
Product Name:Brivudine
Synonyms:Helpin;Uridine,5-[(1E)-2-broMoethenyl]-2'-deoxy-;(E)-(5)-BROMOVINYL-2-DEOXYURIDINE;(E)-5-(2-Bromovinyl)-2'-deoxyuridine;BVDU;(E)-5-(2-BROMOVINYL)-2'-DEOXY-URIDINE;BRIVUDINE;5-(E)-(2-Bromovinyl)-2-deoxyuridine
CAS:69304-47-8
MF:C11H13BrN2O5
MW:333.14
EINECS:1806241-263-5
Product Categories:Inhibitors;API;69304-47-8
Mol File:69304-47-8.mol
Brivudine Structure
Brivudine Chemical Properties
Melting point 165°C
density 1.7800 (rough estimate)
refractive index 1.6520 (estimate)
storage temp. Inert atmosphere,2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
pka8.37±0.10(Predicted)
form Solid
color Off-White
Water Solubility Soluble in water and methanol.
Merck 14,1378
InChIKeyODZBBRURCPAEIQ-CXYVBZRVSA-N
Safety Information
Safety Statements 24/25
WGK Germany 3
RTECS YU7355000
HS Code 29349990
MSDS Information
ProviderLanguage
SigmaAldrich English
Brivudine Usage And Synthesis
Description(E)-5-(2-Bromovinyl)-2'-deoxyuridine is an thymidine analogue and acts as an anti-viral by inhibiting DNA plymerase.
Chemical PropertiesWhite solid
UsesIt is used as pharmaceutical intermediate.
UsesBrivudine is a nucloside analog which causes induction of neuronal differentiation in human reporter cell lines and adult stem cells. Anti-Herpes medication.
Brivudine Preparation Products And Raw materials
Triethoxyvinylsilane ETHYLENE N-Vinyl-2-pyrrolidone 1,2-DIBROMOETHYLENE 5-(BROMOVINYL) 2'-DEOXYURIDINE, [2'-3H]- 5-(BROMOVINYL) 2'-DEOXYURIDINE, [5'-3H]- 5-BROMOVINYL-2'-DEOXYURIDINE, [2-14C]- Doxifluridine sorivudine Vinyl ester resin VINYL PROPIONATE 4-Bromostyrene Vinyl bromide Brivudine (5-[5-(2-BROMOVINYL)-2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-1-YL]-3-HYDROXYTETRAHYDROFURAN-2-YL)METHYL PIVALATE Tris(hydroxymethyl)nitromethane Brimonidine Tartrate Brimonidine
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