5-[ethyl(2-hydroxyethyl)amino]pentan-2-one

5-[ethyl(2-hydroxyethyl)amino]pentan-2-one Basic information
Product Name:5-[ethyl(2-hydroxyethyl)amino]pentan-2-one
Synonyms:5-[ethyl(2-hydroxyethyl)amino]pentan-2-one;5-[Ethyl(2-hydroxyethyl)amino]-2-pentanone;2-Pentanone, 5-[ethyl(2-hydroxyethyl)amino]-;Hydroxychloroquine Sulfate Impurity 31;Hydroxychloroquine sulfate Impurity 26;Hydroxychloroquine Impurity 33
CAS:74509-79-8
MF:C9H19NO2
MW:173.25
EINECS:277-901-2
Product Categories:
Mol File:74509-79-8.mol
5-[ethyl(2-hydroxyethyl)amino]pentan-2-one Structure
5-[ethyl(2-hydroxyethyl)amino]pentan-2-one Chemical Properties
Safety Information
MSDS Information
5-[ethyl(2-hydroxyethyl)amino]pentan-2-one Usage And Synthesis
Uses5-[ethyl(2-hydroxyethyl)amino]pentan-2-one can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Synthesis2.png
30 g of N-ethylethanolamine, 1.2 g of tetrabutylammonium bromide, 25 g of potassium hydroxide, 240 g of chloroform,120g of water was added to the reaction flask, and then the temperature was controlled at 20 to 30 ° C, 38 g of 5-chloro-2-pentanone was added dropwise, and after the addition was completed, the mixture was stirred.Should be 3 hours, static layering, the water phase is discarded, the organic layer is added 24g anhydrous sodium sulfate, the temperature is controlled at 10 ~ 20 ° C, stirred and dried 1Hour, filtration, the filtrate is the organic phase of the condensation product, the content of which is detected, the condensation product is 51.7g, and the molar yield is 94.7% (to 5-Chloro-2-pentanone), GC purity ≧ 98.5%.
5-[ethyl(2-hydroxyethyl)amino]pentan-2-one Preparation Products And Raw materials
Raw materials2-Pentanone, 5-iodo--->5-Chloro-2-pentanone-->2-Acetylbutyrolactone-->2-(Ethylamino)ethanol
Preparation Products2-(4-Aminopentyl(ethyl)amino)ethanol
hydroxygliclazide 7-CHLORO-4-HYDROXY QUINOLINE-3-CARBOXYLIC ACID 5-chloroquinolin-4-ol 5-Chloro-2-pentanone 3,7-Decadiene-2,9-diamine, N,N'-bis(7-chloro-4-quinolinyl)- (9CI) Hydroxychloroquine Sulfate Ethanol, 2-[ethyl[4-(4-quinolinylamino)pentyl]amino]- 2-(Ethylamino)ethanol Hydroxychloroquine Impurity 14 4-aminopentan-1-ol 2-Methylpyrrolidine 7-Quinolinol, 4-[[4-(ethylamino)-1-methylbutyl]amino]- 3-Chloroaniline 4-Quinolinamine, 7-chloro-N-(1-methylbutyl)-

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