ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Glutamic acid derivatives tert-butyl 5-oxo-L-prolinate

tert-butyl 5-oxo-L-prolinate

tert-butyl 5-oxo-L-prolinate Basic information
Product Name:tert-butyl 5-oxo-L-prolinate
Synonyms:L-PyroglutaMic acid ter-butyl ester;L-Pyr-Otbu;L-Proline,5-oxo-, 1,1-diMethylethyl ester;tert-butyl (2S)-5-oxopyrrolidine-2-carboxylate;tert-Butyl L-PyroglutaMate;(S)-tert-Butyl 5-oxopyrrolidine-2-carboxylate;2-Methyl-2-propanyl 5-oxo-L-prolinate;tert-Butyl (S)-5-oxo-2-pyrrolidinecarboxylate
CAS:35418-16-7
MF:C9H15NO3
MW:185.22
EINECS:252-555-5
Product Categories:
Mol File:35418-16-7.mol
tert-butyl 5-oxo-L-prolinate Structure
tert-butyl 5-oxo-L-prolinate Chemical Properties
Melting point 102.0 to 108.0 °C
Boiling point 319.2±35.0 °C(Predicted)
density 1.099±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility soluble in Methanol
pka14.65±0.40(Predicted)
form Powder
color White
BRN 3590226
Safety Information
Hazard Codes Xi
Risk Statements 36/38
Safety Statements 26
WGK Germany 3
HS Code 29339900
MSDS Information
tert-butyl 5-oxo-L-prolinate Usage And Synthesis
Usestert-Butyl (S)-2-pyrrolidone-5-carboxylate can be used:
  • As a starting material/synthon in the synthesis of angiotensin-converting enzyme inhibitors.
  • In the synthesis of phenanthroindolizidine alkaloids named (+)-tylophorine and antofine.
  • As a starting material in the synthesis of radioligands [18F]IUR-1602 and [18F]IUR-1601, applicable for imaging of P2X7R, a therapeutic target for neuroinflammation.

tert-butyl 5-oxo-L-prolinate Preparation Products And Raw materials
tert-Butyl 7-bromoheptanoate tert-butyl 5-bromoindoline-1-carboxylate Carbamic acid, (6-oxohexyl)-, 1,1-dimethylethyl ester TERT-BUTYL 5-BROMOISOINDOLINE-2-CARBOXYLATE tert-Butyl 8-iodooctylcarbamate tert-Butyl 8-oxooctylcarbamate TERT-BUTYL 6-IODOHEXYLCARBAMATE L-Lactide 5-BROMOPENTANOIC ACID, T-BUTYL ESTER tert-butyl(7-oxoheptyl) carbamate Hexanoic acid, 6-bromo-, 1,1-dimethylethyl ester tert-Butyl 9-aminononanoate Ethyl L-pyroglutamate H-PRO-OIPR Methyl L-pyroglutamate H-PRO-OTBU tert-butyl 5-oxo-L-prolinate (S)-N-ALPHA-T-BUTYLOXYCARBONYL-PYROGLUTAMIC ACID T-BUTYL ESTER
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