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| | HEXESTROL Basic information |
| Product Name: | HEXESTROL | | Synonyms: | MESO-3,4-BIS[4-HYDROXYPHENYL]-HEXANE;DIHYDRODIETHYLSTILBESTROL;HEXOESTROL;HEXOESTROLUM;3,4-BIS-(P-HYDROXYPHENYL)-HEXANE;3,4-DI(P-HYDROXYPHENYL)HEXANE;4,4'-(1,2-DIETHYLETHYLENE)DIPHENOL;Esestrolo | | CAS: | 5635-50-7 | | MF: | C18H22O2 | | MW: | 270.37 | | EINECS: | 227-082-2 | | Product Categories: | | | Mol File: | 5635-50-7.mol |  |
| | HEXESTROL Chemical Properties |
| Water Solubility | 11.8mg/L(temperature not stated) |
| Hazard Codes | T | | Risk Statements | 45 | | Safety Statements | 53-45 | | RIDADR | 3249 | | WGK Germany | 2 | | RTECS | SL0560850 | | HazardClass | 6.1(b) | | PackingGroup | III |
| | HEXESTROL Usage And Synthesis |
| Uses | Vitestrol can be used in methods related to bioactive agents that convert from anions to molecules | | Definition | ChEBI: Hexestrol is a stilbenoid. | | Brand name | Synoestrolum. | | World Health Organization (WHO) | Hexestrol is a stilbene derivative. See WHO comment for
diethylstilbestrol.
(Reference: (WHODI) WHO Drug Information, 77.1, 16, 1977) | | Purification Methods | Crystallise meso-Hexestero from *benzene or aqueous EtOH (m 185-188o). The meso-dibenzoyl derivative has m 236-237o. The 3RS,4RS(±)-racemate [5776-72-7] crystallises from pet ether, *C6H6/pet ether, Et2O/pet ether, or MeOH/H2O and has m 128-129o . The (±)-dibenzoyl derivative has m 123-124o . The 3R,4R(+)-isomer [26614-21-1] and 3S,4S(-)-isomer [26614-22-2] crystallise from Et2O/pet ether with m 80 -80.5o and have [] D (+) and (-) 17.7o (c 5, EtOH). Their dibenzoyl derivatives have m 116.5o .[Beilstein 6 III 5503, 6 IV 6761.] They have estrogenic activity where optically active forms are more potent and they have antineoplastic activity. [Aboul-Enein et al. Anal Profiles Drug Subst 11 347 1982, J Am Chem Soc 65 4911941.] |
| | HEXESTROL Preparation Products And Raw materials |
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