2,3,5,6-TETRAFLUORO-4-PYRIDINE-CARBONITRILE

2,3,5,6-TETRAFLUORO-4-PYRIDINE-CARBONITRILE Basic information
Product Name:2,3,5,6-TETRAFLUORO-4-PYRIDINE-CARBONITRILE
Synonyms:4-CYANO-2,3,4,5,6-TETRAFLUOROFLUOROPYRIDINE;2,3,5,6-Tetrafluoropyridine-4-carbonitrile;2,3,5,6-TETRAFLUORO-4-PYRIDINE- CARBONITRILE 99%;2,3,5,6-Tetrafluoropyridine-4-carbonitrile, 4-Cyano-2,3,5,6-tetrafluoropyridine;2,3,5,6-TETRAFLUORO-4-PYRIDINE-CARBONITRILE;4-CYANO-2,3,5,6-TETRAFLUOROPYRIDINE;2,3,5,6-Tetrafluoropyridine-4-carbonitrile, 4-Cyano-2,3,5,6-tetraf;4-Pyridinecarbonitrile, 2,3,5,6-tetrafluoro-
CAS:16297-07-7
MF:C6F4N2
MW:176.07
EINECS:
Product Categories:C6;Heterocyclic Building Blocks;Heterocyclic Compounds;Pyridines
Mol File:16297-07-7.mol
2,3,5,6-TETRAFLUORO-4-PYRIDINE-CARBONITRILE Structure
2,3,5,6-TETRAFLUORO-4-PYRIDINE-CARBONITRILE Chemical Properties
Melting point 66-68 °C (lit.)
Boiling point 166.1±35.0 °C(Predicted)
density 1.56±0.1 g/cm3(Predicted)
pka-14.32±0.28(Predicted)
form crystalline powder
color White
Safety Information
Hazard Codes Xn,Xi
Risk Statements 20/21/22-36/37/38
Safety Statements 26-37/39
WGK Germany 3
Hazard Note Irritant
HS Code 2933399990
MSDS Information
ProviderLanguage
SigmaAldrich English
2,3,5,6-TETRAFLUORO-4-PYRIDINE-CARBONITRILE Usage And Synthesis
Uses2,3,5,6-Tetrafluoro-4-pyridinecarbonitrile may be used in the preparation of 2-anilino-3,5,6-trifluoroisonicotinonitrile.
General Description2,3,5,6-Tetrafluoro-4-pyridinecarbonitrile is a perfluorinated heteroaromatic compound. 2,3,5,6-Tetrafluoro-4-pyridinecarbonitrile (tetrafluoro-4-cyanopyridine) reacts with 1,3-dicarbonyl systems to yield the corresponding [5,6]-ring fused furo derivatives. 2,3,5,6-Tetrafluoro-4-pyridinecarbonitrile (4-cyanotetrafluoropyridine) reacts with amidines to yield [6,6]-fused pyrimidinopyridine system via nucleophilic substitution at the C-3 position of the pyridine ring followed by intramolecular cyclization onto the pendant cyano group. Reaction of 2,3,5,6-tetrafluoro-4-pyridinecarbonitrile (4-cyanotetrafluoropyridine) with sulfur centred nucleophiles has been reported.
2,3,5,6-TETRAFLUORO-4-PYRIDINE-CARBONITRILE Preparation Products And Raw materials
Raw materials2,3,5,6-TETRACHLOROISONICOTINONITRILE-->4-Cyanopyridine-->sodium:cyanide-->Pentafluoropyridine
Preparation ProductsBENZOYL FLUORIDE
3-Fluoropyridine-4-carbonitrile 4-Cyanopyridine 2-Fluoropyridine 2,3,5,6-Tetrafluoropyridine 2-Fluoro-4-methylpyridine 3,5-Difluoropyridine 2,6-DIFLUORO-4-CYANO-PYRIDINE 2,5-Difluoropyridine 2,3,5,6-TETRAFLUORO-4-PYRIDINE-CARBONITRILE 3-Fluoropyridine 2,6-Difluoropyridine 3-Fluoro-4-methylpyridine 2,3,5-Trifluoropyridine 2-FLUOROISONICOTINONITRILE 2,3,6-TRIFLUOROPYRIDINE 2,3-Difluoropyridine 2 3 5 6-TETRAFLUORO-4-METHYLPYRIDINE 9&

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