Chloroacetamide

Chloroacetamide Basic information
Product Name:Chloroacetamide
Synonyms:KM 101;NSC 54286;NSC 8408;2-ChloroacetaMide >=98.0% (HPLC);Piracetam Imp. B;chloroacetylamine;Mergal AF;mergalaf
CAS:79-07-2
MF:C2H4ClNO
MW:93.51
EINECS:201-174-2
Product Categories:Amines;Inhibitors;API Intermediate;Building Blocks;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks;Amides;Carbonyl Compounds;Organic Building Blocks;Chloroacetamide SKY;Halogenated Heterocycles ,Piperazines
Mol File:79-07-2.mol
Chloroacetamide Structure
Chloroacetamide Chemical Properties
Melting point 116-118 °C(lit.)
Boiling point 224.5 °C
density 0.84
vapor pressure 0.05 mm Hg ( 20 °C)
refractive index 1.4480 (estimate)
Fp 170 °C
storage temp. Store below +30°C.
solubility methanol: soluble1g/10 mL
form Crystalline Powder
pka14.69±0.40(Predicted)
color White
PH3.8-4.1 (40g/l, H2O, 20℃)
Water Solubility Soluble in water(90g/L).
Merck 14,2110
BRN 878191
InChIKeyVXIVSQZSERGHQP-UHFFFAOYSA-N
LogP-0.530
CAS DataBase Reference79-07-2(CAS DataBase Reference)
NIST Chemistry ReferenceAcetamide, 2-chloro-(79-07-2)
EPA Substance Registry SystemAcetamide, 2-chloro- (79-07-2)
Safety Information
Hazard Codes T
Risk Statements 25-43-62
Safety Statements 22-36/37-45
RIDADR UN 2811 6.1/PG 3
WGK Germany 2
RTECS AB5075000
TSCA Yes
HazardClass 6.1
PackingGroup III
HS Code 29241900
Hazardous Substances Data79-07-2(Hazardous Substances Data)
ToxicityLD50 orally in Rabbit: 138 mg/kg LD50 dermal Rat > 2000 mg/kg
MSDS Information
ProviderLanguage
2-Chloroacetamide English
SigmaAldrich English
ACROS English
ALFA English
Chloroacetamide Usage And Synthesis
DescriptionChloroacetamide is a preservative used in several applications such as in cutting metalwork fluids, in paints or in glues. It can induce contact dermatitis in hairdressers, or in shoemakers when used as a leather preservative.
Chemical Propertieswhite crystalline powder
UsesA component of herbicidal mixtures of cellulose biosynthesis inhibitors with VLCFA inhibitors.
Usespreservative in cosmetic and pharmaceutical creams, shampoos, bath lotions, etc.; preservative in glues, cooling fluids.
Uses2-Chloroacetamide is used as surface-active agent in home laundry, cleaning products & household formulated cleaners, other industrial uses, petroleum production, polymer processing.
Flammability and ExplosibilityNonflammable
Contact allergensChloroacetamide as a preservative is used in several applications as in cutting metalworking fluids, in paints or in glues. It can induce contact dermatitis in hairdressers or in shoemakers, being used as a leather preservative.
Safety ProfilePoison by ingestion, intravenous, and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits very toxic Cland NOx. See also N-CHLOROACETAMIDE.
Purification MethodsRecrystallise the amide from acetone and dry it under vacuum over P2O5. [Beilstein 2 IV 490.]
N-[3-(4-TERT-BUTYLBENZOYL)-4,5,6,7-TETRAHYDRO-1-BENZOTHIEN-2-YL]-2-CHLOROACETAMIDE 5-CHLORO-2'-DEOXYURIDINE 2,1,3-BENZOTHIADIAZOL-7-YL-2-CHLOROACETAMIDE 2-chloro-n-naphthalen-1-yl-acetamide 2-CHLOROPROPIONAMIDE Dichloroacetamide 1-PHENYL-4,5-DICHLORO-6-PYRIDAZONE LABOTEST-BB LT00441005 DIACETAMIDE N-(4-[[(2E)-AZEPAN-2-YLIDENEAMINO]SULFONYL]PHENYL)-2-CHLOROACETAMIDE N-(2-ACETYL-1-BENZOFURAN-3-YL)-2-CHLOROACETAMIDE dichloroacetyl isocyanate N-[3-(1,3-BENZOTHIAZOL-2-YL)PHENYL]-2-CHLOROACETAMIDE N-{3-(4-BROMOPHENYL)-1-[4-(4-METHOXYPHENYL)-1,3-THIAZOL-2-YL]-1H-PYRAZOL-5-YL}-2-CHLOROACETAMIDE 2-Chloro-N-[4-chloro-2-(2-chlorobenzoyl)phenyl]acetamide N-Methylolchloroacetamide N-{3-(4-BROMOPHENYL)-1-[4-(4-CHLOROPHENYL)-1,3-THIAZOL-2-YL]-1H-PYRAZOL-5-YL}-2-CHLOROACETAMIDE CHLOROACETYL-L-TYROSINE

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