Oxamic acid

Oxamic acid Basic information
Product Name:Oxamic acid
Synonyms:AMINOOXOACETIC ACID;Oxamicacid,98%;Aminooxoacetic acid, Oxalic acid monoamide;OxaMic acid, 98% 10GR;OxaMic acid, 98% 25GR;Acetic acid, aminooxo-;aminooxo-aceticaci;Formic acid, (aminocarbonyl)-
CAS:471-47-6
MF:C2H3NO3
MW:89.05
EINECS:207-443-0
Product Categories:
Mol File:471-47-6.mol
Oxamic acid Structure
Oxamic acid Chemical Properties
Melting point 207-210 °C (dec.) (lit.)
Boiling point 165.08°C (rough estimate)
density 1.6193 (rough estimate)
refractive index 1.4264 (estimate)
storage temp. 2-8°C(protect from light)
solubility DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form Crystalline Powder
pka1.60±0.20(Predicted)
color White
Water Solubility Soluble in water 108 mg/mL.
Merck 14,6917
BRN 1743294
InChIInChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)
InChIKeySOWBFZRMHSNYGE-UHFFFAOYSA-N
SMILESC(O)(=O)C(N)=O
CAS DataBase Reference471-47-6(CAS DataBase Reference)
EPA Substance Registry SystemOxamic acid (471-47-6)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
TSCA Yes
HS Code 29241990
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
Oxamic acid Usage And Synthesis
Chemical PropertiesOxamic acid is a white, water-soluble solid. It is the monoamide ofoxalic acid. It can react with metal carbonates to form oxamate. Oxamic acid inhibits lactate dehydrogenase A.
UsesOxamic acid is an ozone oxidation product and is used in the synthesis of hydroxybenzimidazoles preparation as potential anti tumor agents targeting human lactate dehydrogenase A.This compound is suitable for lactate dehydrogenase (LDH) related research.
DefinitionChEBI: Oxamic acid is a dicarboxylic acid monoamide resulting from the formal condensation of one of the carboxy groups of oxalic acid with ammonia. It has a role as an Escherichia coli metabolite. It is a conjugate acid of an oxamate.
ApplicationOxamic acid (OA) has applications in polymer chemistry. It increases the water solubility of certain polymers, including polyester,epoxide, and acrylic upon binding with them. Oxamic acid can be used as a reactant to prepare 6-phenanthridinecarboxamide by direct C-H carbamoylation reaction using ammonium persulfate in DMSO. It can also be used as an organic ligand to prepare functionalized metal oxide nanoparticles for various biological applications. OA along with p-aminobenzoic acid is used to functionalize Au nanoparticles for the development of a sensor to detect Fe3+ ions by the calorimetric method.
oxanilic acid ETHYL 2-OXO-2-(4-TOLUIDINO)ACETATE N-(4-(1,4-benzodioxan-6-yl)-2-thiazolyl)oxamic acid N-(4-aminophenyl)oxamic acid,N-(P-AMINOPHENYL)OXAMIC ACID BETA-N-OXALYLAMINO-L-ALANINE ETHYL N,N-DIETHYLOXAMATE N-BUTYL HYDRAZINE OXALATE 3-OXALURIC ACID N-(4-CHLORO-PHENYL)-OXALAMIC ACID ETHYL ESTER METHYL 3-[2-(2-ETHOXY-2-OXOACETYL)HYDRAZINO]THIOPHENE-2-CARBOXYLATE Oxamic acid, (tetrahydro-2-imino-5-oxo-4-imidazolyl)- (4CI) (3-Amino-1-carboxypropyl)oxamic acid ETHYL 1-PIPERIDINEGLYOXYLATE OXAMIC ACID POTASSIUM SALT Oxamic acid, 6-benzothiazolyl- (6CI) OXAMIC ACID N-BUTYL ESTER ETHYL 2-([1-(4-CHLOROPHENYL)-1-METHYL-1-OXO-LAMBDA6-SULFANYLIDENE]AMINO)-2-OXOACETATE OXAMIC ACID ETHYL ESTER,Oxamic acid ethyl

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