ChemicalBook Product Catalog Chemical Reagents Organic reagents Acyl halide Phthalylglycyl chloride

Phthalylglycyl chloride

Phthalylglycyl chloride Basic information
Product Name:Phthalylglycyl chloride
Synonyms:Phthalyl-glycyl chloride ,98%;(1,3-Dioxo-2H-isoindole-2-yl)acetyl chloride;1,3-Dihydro-1,3-dioxo-2H-isoindole-2-acetic acid chloride;2-(Phthalimidyl)acetyl chloride;2-Phthalimidylacetic acid chloride;N-(2-Chloro-2-oxoethyl)phthalimide;N,N-Phthaloylglycine chloride;2-(1,3-dioxoisoindolin-2-yl) acetyl chloride
CAS:6780-38-7
MF:C10H6ClNO3
MW:223.61
EINECS:229-840-8
Product Categories:Acid Halides;Carbonyl Compounds;Organic Building Blocks;pharmacetical;Acid Halides;Building Blocks;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks;Heterocycle-other series
Mol File:6780-38-7.mol
Phthalylglycyl chloride Structure
Phthalylglycyl chloride Chemical Properties
Melting point 84-85 °C
Boiling point 190-192 °C(Press: 15 Torr)
density 1.504±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility Chloroform, Dichloromethane
form Solid
pka-2.56±0.20(Predicted)
color White
Safety Information
Hazard Codes T
Risk Statements 25-34
Safety Statements 26-36/37/39-45
RIDADR UN 2923 8/PG 3
WGK Germany 3
HazardClass IRRITANT
MSDS Information
ProviderLanguage
SigmaAldrich English
Phthalylglycyl chloride Usage And Synthesis
Chemical Propertiesslight yellow to white crystalline powder
UsesPhthalylglycyl chloride can be used in the synthesis of N-Phthalimidoacetyl-β-phenylethylamnine.
UsesReactant involved in:• ;Synthesis of selenium-containing amino acid analogs with bactericidal and antifungal activity1• ;Photoinduced single electron transfer cyclization for preparation of cyclic peptides2• ;Arndt-Eistert synthesis3• ;Mitsunobu and arbuzov-type multicomponent pathway4• ;Remote C-H bond functionalization5• ;Amido-alkylation for synthesis of benzofuran derivatives6
General DescriptionPhthalylglycyl chloride can be synthesized via reaction of phthalyl-glycine with thionyl chloride.
Phthalylglycyl chloride Preparation Products And Raw materials
Preparation ProductsH-GLY-CYS-OH-->6-(Phthalimidomethyl)morphanthridine-->PHT-GLY-ONP-->Phthaloylgly Cylglycine
N-(2-CHLOROETHYL)BENZAMIDE O-Phthalimide Phthalhydrazide N-(2-CHLOROETHYL)PHTHALIMIDE o-Toluoyl chloride Phthalylglycyl chloride Acetyl coenzyme A sodium salt Isophthaloyl dichloride Pivaloyl chloride Ammonium chloride N-Phthaloylglycine ACETYLACETONATE N-(2-CHLOROETHYL)ACETAMIDE Dihydromyrcenol 2-(1,3-DIOXO-1,3-DIHYDRO-ISOINDOL-2-YL)-PROPIONYL CHLORIDE Potassium phthalimide 2-​[[(2-​ethylphenyl)​(2-​hydroxyethyl)​amino]​methyl]​-​3,​3-​difluoro-Propanenitrile 2-Chlorobenzoyl chloride
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