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| | 1-Bromo-2-nitrobenzene Basic information |
| | 1-Bromo-2-nitrobenzene Chemical Properties |
| Melting point | 40-42 °C (lit.) | | Boiling point | 261 °C (lit.) | | density | 1.7 g/cm3 (20℃) | | refractive index | 1.6060 (estimate) | | Fp | >230 °F | | storage temp. | 2-8°C | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | powder to crystal | | color | Light yellow to Amber to Dark green | | Water Solubility | insoluble | | BRN | 2044109 | | Stability: | Stable. Combustible. Incompatible with strong bases, strong oxidizing agents. | | CAS DataBase Reference | 577-19-5(CAS DataBase Reference) | | NIST Chemistry Reference | Benzene, 1-bromo-2-nitro-(577-19-5) | | EPA Substance Registry System | o-Bromonitrobenzene (577-19-5) |
| | 1-Bromo-2-nitrobenzene Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powder | | Uses | 1-Bromo-2-nitrobenzene is used in organic synthesis. It also can react with 2-methylamino-benzoic acid to get N-methyl-N-(2-nitro-phenyl)-anthranilic acid. And it is also used in the preparation of 4-methoxy-2?-nitrodiphenyl ether, 1-methoxy-3,5-bis-(2-nitro-phenoxy)benzene. | | Uses | 1-Bromo-2-nitrobenzene may be used in the preparation of:
- 4-methoxy-2′-nitrodiphenyl ether
- 1-methoxy-3,5-bis-(2-nitro-phenoxy)benzene
- 5-hydroxy-3-methoxy-2′-nitrodiphenyl ether
| | General Description | 1-Bromo-2-nitrobenzene undergoes palladium[0]-mediated Ullmann cross-coupling reaction with a range of β-halo-enals, -enones or -esters to afford the corresponding β-aryl derivatives. Palladium[0]-mediated Ullmann cross-coupling reaction of 1-bromo-2-nitrobenzene with β-bromo-α,β-unsaturated aldehydes is reported. | | Purification Methods | Crystallise it twice from pet ether, using charcoal before the first crystallisation. [Beilstein 5 III 618, 5 IV 728.] |
| | 1-Bromo-2-nitrobenzene Preparation Products And Raw materials |
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