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| | Perfluorodecalin Basic information |
| Product Name: | Perfluorodecalin | | Synonyms: | 1,1,2,2,3,3,4,4,4a,5,5,6,6,7,7,8,8,8a-Octadecafluorodecahydronaphthalene;decahydrooctadecafluoro-naphthalen;F-DC;Naphthalene, octadecafluorodecahydro-;octadecafluorodecahydro-naphthalen;Octadecafluorodecaline;perflunafene;Perfluorodecalin (PFD, Perflunafene, Octadecaflourodecahydronaphtalene (CIS+Trans), 95% (Perftordecalin)) | | CAS: | 306-94-5 | | MF: | C10F18 | | MW: | 462.08 | | EINECS: | 206-192-4 | | Product Categories: | Fluorinated Building Blocks;Halogenated Hydrocarbons;Alkyl Fluorinated Building Blocks;Organic Building Blocks;Organic Fluorinated Building Blocks;Other Fluorinated Organic Building Blocks;Purine;Fluorous Chemistry;Fluorous Solvents;Synthetic Organic Chemistry;Aryl;Building Blocks;C9 to C12;Chemical Synthesis;organofluorine compounds | | Mol File: | 306-94-5.mol |  |
| | Perfluorodecalin Chemical Properties |
| Melting point | -10 °C (lit.) | | Boiling point | 142 °C (lit.) | | density | 1.908 g/mL at 25 °C (lit.) | | vapor density | 17.5 (vs air) | | vapor pressure | 8.8hPa at 25℃ | | refractive index | n20/D 1.3145(lit.) | | Fp | >230 °F | | storage temp. | Store below +30°C. | | form | Liquid | | color | Clear colorless | | Specific Gravity | 1.908 | | Water Solubility | Insoluble | | Merck | 14,4183 | | BRN | 2067113 | | InChIKey | UWEYRJFJVCLAGH-UHFFFAOYSA-N | | LogP | 5.02-666 at 25℃ | | CAS DataBase Reference | 306-94-5(CAS DataBase Reference) | | NIST Chemistry Reference | Perflunafene(306-94-5) | | EPA Substance Registry System | Perfluorodecalin (306-94-5) |
| Hazard Codes | Xi,F | | Risk Statements | 10 | | Safety Statements | 23-24/25-41-16 | | RIDADR | UN 1993 3/PG 3 | | WGK Germany | 3 | | RTECS | QJ3175000 | | Hazard Note | Irritant | | TSCA | T | | HazardClass | 3.2 | | PackingGroup | III | | HS Code | 29038900 | | Toxicity | LD50 ivn-mus: 50 mg/kg PGPKA8 27(10),8,82 |
| | Perfluorodecalin Usage And Synthesis |
| Description | Perfluorodecalin (PFD) is a chemically and biologicallyinert biomaterial and, as many perfluorocarbons, is alsohydrophobic, radiopaque and has a high solute capacity forgases such as oxygen.
Perfluorodecalin is a fluorocarbon and derivative of decalin, and used in cosmetics and beauty products as to dissolve and deliver oxygen to the skin in formulas (Wikipedia). It is also used as a skin conditioning agent, detangler, and solvent in some formulas. Perfluorodecalin's ability to dissolve oxygen is thought to revitalize skin and reduce wrinkles, increasing the partial pressure of oxygen (pO2), according to research.
Some studies have shown that formulas that include Perflurodecalin improve the skin's barrier function resulting in increased moisturizing efficacy. However, there are no studies to prove that added oxygen can actually repair wrinkled skin or prevent lines from forming. Conversely, too much oxygen can enhance the number of unstable oxygen molecules which cause free radical damage. | | Chemical Properties | clear colourless liquid | | Uses | Perfluorodecalin is a fluorous solvent generally used as a primary component of the fluorous biphasic system (FBS) or the fluorous multiphasic system (FMS) in synthetic chemistry. It is also used as an additive to increase oxygen solubility in fermentation media. | | Uses | Perfluorodecalin is used as a building block reagent as well maintains ability to dissolve gases such as oxygen and increase oxygen to a location allowing for medicinal uses such as preserving tissue after pancreas transplants. | | Definition | ChEBI: A fluorocarbon that is decalin in which every hydrogen is replaced by fluorine. Capable of dissolving large quantities of oxygen, it has been used as the basis of an artificial blood substitute. | | Safety Profile | Poison by intravenous route. When heated to decomposition it emits toxic vapors of Fí. |
| | Perfluorodecalin Preparation Products And Raw materials |
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