(2S,4R)-Teneligliptin

(2S,4R)-Teneligliptin Basic information
Product Name:(2S,4R)-Teneligliptin
Synonyms:Teneligptin API;((2S,4R)-4-(4-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl)pyrrolidin-2-yl)(thiazolidin-3-yl)Methanone;Teneligliptin (2S,4R)-Isomer;[(2S,4R)-4-[4-(5-methyl-2-phenylpyrazol-3-yl)piperazin-1-yl]pyrrolidin-2-yl]-(1,3-thiazolidin-3-yl)methanone;3-{(2S,4R)-4-[4-(3-Methyl-1-phenyl-1H- pyrazol-5-yl)piperazin-1-yl]pyrrolidin -2-yl-carbonyl}thiazolidine;Methanone, [(2S,4R)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-1-piperazinyl]-2-pyrrolidinyl]-3-thiazolidinyl-;Teneligliptin 2S,4R;Teneligliptin (2S,4R)-Isomer Impurity
CAS:1404559-15-4
MF:C22H30N6OS
MW:426.58
EINECS:
Product Categories:
Mol File:1404559-15-4.mol
(2S,4R)-Teneligliptin Structure
(2S,4R)-Teneligliptin Chemical Properties
Boiling point 663.4±55.0 °C(Predicted)
density 1.38±0.1 g/cm3(Predicted)
pka8.70±0.10(Predicted)
Safety Information
MSDS Information
(2S,4R)-Teneligliptin Usage And Synthesis
Uses(2S,4R)-Teneligliptin is a stereoisomer of Teneligliptin (T018300, HBr); a dipeptidyl peptidase-4 (DPP-4) inhibitor that is used to treat type 2 diabetes. It is eliminated via excretion and has a half-life of 24.2 hours in the human body.
(2S,4R)-Teneligliptin Preparation Products And Raw materials
Teneligliptin Carboxylic Acid Impurity Teneligliptin Teneligliptin Hydrobromide 1-Pyrrolidinecarboxylic acid, 4-oxo-2-(3-thiazolidinylcarbonyl)-, 1,1-diMethylethyl ester, (2R)- Teneligliptin D8 1-Pyrrolidinecarboxylic acid, 4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-1-piperazinyl]-2-(3-thiazolidinylcarbonyl)-, 1,1-dimethylethyl ester, (2S,4R)- N-DesMethyl TelMisartan propyl[2,6'-bi-1H-benzimidazol]-1'-yl]methyl]- Teneligliptin (2R,4R)-Isomer Teneligliptin (2R,4S)-Isomer 2-aMino-3-Methyl-3-sulfino-4-(1H-1,2,3-triazol-1-yl)butyric acid Tazobactam diastereomer

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