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Edaravone

Edaravone Basic information
Product Name:Edaravone
Synonyms:3,3'',5'-trimethyl-1,1'',2'-triphenyl- 1H,1''H-[4,4':4',4''-terpyrazole]- 3',5,5''(2'H,4H,4''H)-trione;5,5',5''-Trimethyl-2,2',2''-triphenyl-[4,4':4',4''-ter-4H-pyrazole]-3,3',3''(2H,2'H,2''H)-trione;Edaravone impurity 3/Edaravone Trimer 1/2,4-Dihydro-4,4-bis(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)-5-methyl-2-phenyl-3H-pyrazol-3-one;3,3'',5'-trimethyl-1,1'',2'-triphenyl;5,5',5''-Trimethyl-2,2',2''-triphenyl-2,2'',4,4''-tetrahydro-3H,3''H-[4,4':4',4''-terpyrazole]-3,3',3''(2'H)-trione;[4,4':4',4''-Ter-4H-pyrazole]-3,3',3''(2H,2'H,2''H)-trione, 5,5',5''-trimethyl-2,2',2''-triphenyl- (9CI);4,4-Bis-(3-methyl-phenyl-pyrazolin-5-on-4-yl)-3-methyl-1-phenyl-pyrazolin-5-on;5-methyl-4,4-bis(3-methyl-5-oxo-1-phenyl-4H-pyrazol-4-yl)-2-phenylpyrazol-3-one
CAS:68195-63-1
MF:C30H26N6O3
MW:518.57
EINECS:
Product Categories:
Mol File:68195-63-1.mol
Edaravone Structure
Edaravone Chemical Properties
Melting point 200 °C (decomp)(Solv: ethanol (64-17-5))
Boiling point 770.6±60.0 °C(Predicted)
density 1.34±0.1 g/cm3(Predicted)
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka2.15±0.70(Predicted)
color White to Off-White
Safety Information
MSDS Information
Edaravone Usage And Synthesis
UsesEdaravone Trimer is an impurity of Edaravone ( ). Edaravone is an intravenous medication used to help with recovery following a stroke and to treat amyotrophic lateral sclerosis.
Edaravone Preparation Products And Raw materials
Preparation ProductsBISPYRAZOLONE
1,2-Dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one 4,5-dihydro-a-(hydroxyMethyl)-a,3-diMethyl-5-oxo-1-phenyl-1H-Pyrazole-4-Methanesulfonic acid 1H-Pyrazole, 5-methoxy-3-methyl-1-phenyl- Edaravone Impurity 14 Edaravone Impurity 26 Edaravone Impurity 5 Edaravone Impurity 8 ethyl 3-acetoxy-2-butenoate Ethyl (3E)-3-(2-phenylhydrazin-1-ylidene)butanoate Edaravone Impurity 15 Edaravone Impurity 19 1H-Pyrazole,3-ethoxy-5-methyl-1-phenyl-(9CI) NSC4751 1-(Bromophenylmethyl)-4-chlorobenzene 4,5-Dihydro-α,3-diMethyl-5-oxo-1-phenyl-α-sulfo-1H-pyrazole-4-acetic Acid Edaravone iMpurity P3 3H-Pyrazol-3-one, 2,4-dihydro-4,4-bis(5-hydroxy-3-Methyl- 1-phenyl-1H-pyrazol-4-yl)-5-Methyl-2-phenyl- 3,3'-diMethyl-1,1'-diphenyl-1H,1'H-4,4'-bipyrazole-5,5'-diol
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