IMp. E (EP): 1,4-Bis(diphenylMethyl)piperazine

IMp. E (EP): 1,4-Bis(diphenylMethyl)piperazine Basic information
Product Name:IMp. E (EP): 1,4-Bis(diphenylMethyl)piperazine
Synonyms:IMp. E (EP): 1,4-Bis(diphenylMethyl)piperazine;Cinnarizine EP IMpurity E;Cinnarizine IMpurity E;1,4-Dibenzhydrylpiperazine dihydrochloride;1,4-bis-(Diphenylmethyl)piperazine;Cinnarizine Impurity 5(Cinnarizine EP Impurity E);1,4-Bis(benzhydryl)piperazine;Piperazine, 1,4-bis(diphenylmethyl)-
CAS:216581-01-0
MF:C30H30N2
MW:418.57
EINECS:
Product Categories:
Mol File:216581-01-0.mol
IMp. E (EP): 1,4-Bis(diphenylMethyl)piperazine Structure
IMp. E (EP): 1,4-Bis(diphenylMethyl)piperazine Chemical Properties
Melting point >235°C (dec.)
Boiling point 526.2±45.0 °C(Predicted)
density 1.122±0.06 g/cm3(Predicted)
storage temp. Amber Vial, Refrigerator, Under inert atmosphere
solubility Chloroform (Slightly), DMSO (Slightly, Heated)
form Solid
pka6.17±0.10(Predicted)
color White to Off-White
Stability:Light Sensitive
Safety Information
MSDS Information
IMp. E (EP): 1,4-Bis(diphenylMethyl)piperazine Usage And Synthesis
Uses1,4-Bis(benzhydryl)piperazine is a cinnarizine (C465300) impurity. Cinnarizine is an anti-vasoconstricting agent (1), as well as a calcium channel blocker (2,3) with antiallergic activity. Antihistaminic.
IMp. E (EP): 1,4-Bis(diphenylMethyl)piperazine Preparation Products And Raw materials
Flunarizine Fluoro hydrochloride Cinnarizine Capsules 1-(DiphenylMethyl)-4-[(1RS,3E)-4-phenyl-1-[(E)-2-phenylethenyl)-3-buten-1-yl]piperazine IMp. C (EP): (4-(DiphenylMethyl)-1,1-bis[(E)-3-phenylprop-2-enyl]piperaziniuM Chloride Stugeron 1-BENZHYDRYLPIPERAZINE (Z)-Cinnarizine

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