ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyridine compound Chloropyridine N-(3,5-Dichloro-4-pyridinyl)-3,4-bis(difluoroMethoxy)benzaMide

N-(3,5-Dichloro-4-pyridinyl)-3,4-bis(difluoroMethoxy)benzaMide

N-(3,5-Dichloro-4-pyridinyl)-3,4-bis(difluoroMethoxy)benzaMide Basic information
Product Name:N-(3,5-Dichloro-4-pyridinyl)-3,4-bis(difluoroMethoxy)benzaMide
Synonyms:N-(3,5-dichloropyridin-4-yl)-3,4-bis(difluoroMethoxy)benzaMide;3,4-Bis(difluoroMethoxy) RofluMilast;N-(3,5-Dichloro-4-pyridinyl)-3,4-bis(difluoroMethoxy)benzaMide;BenzaMide, N-(3,5-dichloro-4-pyridinyl)-3,4-bis(difluoroMethoxy)-;RofluMilast IMpurity 2;Roflumilast Impurity H;Roflumilast-5;3,4-bis(difluoroMethoxy)benzaMide
CAS:162401-30-1
MF:C14H8Cl2F4N2O3
MW:399.12
EINECS:
Product Categories:Imidazolines/Imidazolidines ,Imidazoles
Mol File:162401-30-1.mol
N-(3,5-Dichloro-4-pyridinyl)-3,4-bis(difluoroMethoxy)benzaMide Structure
N-(3,5-Dichloro-4-pyridinyl)-3,4-bis(difluoroMethoxy)benzaMide Chemical Properties
Boiling point 377.9±42.0 °C(Predicted)
density 1.559±0.06 g/cm3(Predicted)
pka9.62±0.70(Predicted)
Safety Information
MSDS Information
N-(3,5-Dichloro-4-pyridinyl)-3,4-bis(difluoroMethoxy)benzaMide Usage And Synthesis
Uses3,4-Bis(difluoromethoxy) Roflumilast is an impurity of the antiasthmatic drug Roflumilast (R639700).
N-(3,5-Dichloro-4-pyridinyl)-3,4-bis(difluoroMethoxy)benzaMide Preparation Products And Raw materials
3-Cyclopropylmethoxy-4-difluoromethoxy-benzoic acid benzaMide, N-(3,5-dichloro-4-pyridinyl)-4-(difluoroMethoxy)-3-hydroxy- 4-Amino-3,5-dichloropyridine RofluMilast related substance RofluMilast related substance Roflumilast RofluMilast N-Oxide 4-Amino-3,5-dichloropyridine N-oxide Roflumilast-d3 Roflumilast N-oxide D4 Roflumilast-d4 Roflumilast Impurity 14 BenzaMide, 3,4-bis(cyclopropylMethoxy)-N-(3,5-dichloro-4-pyridinyl)- RofluMilast related substance Roflumilast 3,5-DICHLORO-4-AMINOPYRIDINE N-(3-Chloropyridin-4-yl)-3-(cyclopropylMethoxy)-4-(difluoroMethoxy)benzaMide 4-(DIFLUOROMETHOXY)-3-(CYCLOPROPYLMETHOXY)-BENZALDEHYDE
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