ChemicalBook Product Catalog Chemical Reagents Organic reagents Acyl halide 2-Chloropropionyl chloride

2-Chloropropionyl chloride

2-Chloropropionyl chloride Basic information
Description
Product Name:2-Chloropropionyl chloride
Synonyms:2-chloro-propanoylchlorid;2-chloro-Propanoylchloride;Propanoyl chloride, 2-chloro-;Propanoylchloride,2-chloro-;ALPHA-CHLOROPROPIONYL CHLORIDE;2-CHLOROPROPIONIC ACID CHLORIDE;2-CHLOROPROPIONYL CHLORIDE;alpha-Chloropropionyl
CAS:7623-09-8
MF:C3H4Cl2O
MW:126.97
EINECS:231-540-7
Product Categories:Imidazoles;Acid Halides;Building Blocks;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks;API Intermediate;Acid Halides;Carbonyl Compounds;Organic Building Blocks
Mol File:7623-09-8.mol
2-Chloropropionyl chloride Structure
2-Chloropropionyl chloride Chemical Properties
Melting point -71 °C
Boiling point 109-111 °C (lit.)
density 1.308 g/mL at 25 °C (lit.)
refractive index n20/D 1.440(lit.)
Fp 88 °F
storage temp. Flammables area
solubility soluble in Chloroform
form Liquid
color Clear colorless to light yellow
Water Solubility MAY DECOMPOSE
BRN 605452
Stability:Moisture Sensitive, Volatile
InChIKeyJEQDSBVHLKBEIZ-UHFFFAOYSA-N
CAS DataBase Reference7623-09-8(CAS DataBase Reference)
NIST Chemistry ReferenceAlpha-chloropropionyl chloride(7623-09-8)
EPA Substance Registry SystemPropanoyl chloride, 2-chloro- (7623-09-8)
Safety Information
Hazard Codes C
Risk Statements 10-35-37
Safety Statements 26-36/37/39-45-25-16
RIDADR UN 2920 8/PG 2
WGK Germany 3
TSCA Yes
HazardClass 8
PackingGroup II
HS Code 29159000
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
2-Chloropropionyl chloride Usage And Synthesis
Description2-Chloropropionyl Chloride is used as a reagent in the synthesis of pyrazolo[3,4-d]pyrimidines as anti-inflammatory and analgesic agents. It is used as a reagent in the chemical surface fictionalization of parylene C. It is used in the synthesis of (±)-mintlactone, in the preparation of a poly(ethylene glycol) macro initiator & chlorine modified TiO2 nanoparticles, the ATRP initiators.
Chemical Propertiesclear colorless to light yellow liquid
Uses2-Chloropropionyl chloride was used:
  • as reagent in the chemical surface functionalization of parylene C
  • in the preparation of a poly(ethylene glycol) macroinitiator, required for the atom transfer radical polymerization (ATRP) of styrene
  • in the synthesis of (±)-mintlactone
  • in the preparation of chlorine modified TiO2 nanoparticles, the ATRP initiators
Uses2-Chloropropionyl chloride is used as a reagent in the chemical surface fictionalization of parylene C. It is used in the synthesis of (±)-mintlactone, in the preparation of a poly(ethylene glycol) macro initiator & chlorine modified TiO2 nanoparticles, the ATRP initiators.
2-CHLOROTETRAFLUOROPROPANOYL CHLORIDE 2,3-DICHLOROPROPIONYL CHLORIDE (-)-ALPHA-CHLOROPHENYLACETYL CHLORIDE 2-CHLOROPROPIONYL-2,3,3,3-D4 CHLORIDE Fludarabine Phosphate α-Chloropropionyl Chloride 2-CHLOROPROPIONYL CHLORIDE [1-14C] [R,(-)]-2-Chloropropionyl chloride Propionyl chloride 2-CHLOROISOBUTYRYL CHLORIDE [S,(+)]-2-Chloropropionyl chloride 2-CHLOROBUTYRYL CHLORIDE 2-CHLORO-2-PHENYLACETYL CHLORIDE 2-Chloropropionyl chloride A-CHLOROPROPIONYL CHLORIDE Hydrocinnamoyl chloride 2-CHLORO-2,2-DIPHENYLACETYL CHLORIDE alpha-chloroproionyl chloride 2-​[[(2-​ethylphenyl)​(2-​hydroxyethyl)​amino]​methyl]​-​3,​3-​difluoro-Propanenitrile
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