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5'-Epi-LaMivudine

5'-Epi-LaMivudine Basic information
Product Name:5'-Epi-LaMivudine
Synonyms:5'-Epi-LaMivudine;2'-Epi-LaMivudine;(2S-trans)-4-AMino-1-[2-(hydroxyMethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyriMidinone;4-AMino-1-[(2S,5S)-2-(hydroxyMethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyriMidinone;trans(-)-2-HydroxyMethyl-5-(cytosin-1-yl)-1,3-oxathiolane;Lamivudine Impurity 4 (Lamivudine Diastereoisomer);Lamivudine Diastereoisomer;Lamivudine 2-Epimer
CAS:136846-20-3
MF:C8H11N3O3S
MW:229.26
EINECS:
Product Categories:Amines, Anti-virals, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds;Amines;Anti-virals;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
Mol File:136846-20-3.mol
5'-Epi-LaMivudine Structure
5'-Epi-LaMivudine Chemical Properties
Melting point 172.6 °C(Solv: water (7732-18-5); methanol (67-56-1))
Boiling point 475.4±55.0 °C(Predicted)
density 1.73±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO (Slightly), Water (Slightly)
form Solid
pka13.83±0.10(Predicted)
color Off-White to Pale Yellow
Safety Information
MSDS Information
5'-Epi-LaMivudine Usage And Synthesis
Uses2’-Epi-Lamivudine (Lamivudine EP Impurity B) is an epimer of Lamivudine (L172500); an antiviral that inhibits HIV-reverse transcriptase.
5'-Epi-LaMivudine Preparation Products And Raw materials
(2R-cis)-5-(4-aMino-2-oxo-1(2H)-pyriMidinyl)-1,3-oxathiolane-2-carboxylic Acid Aids004768 Lamivudine Salicylic acid lamivudine sulfoxide Lamivudine Impurity 1 Cytosine 4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one ent-LaMivudine Uracil
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