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| | 5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Basic information |
| Product Name: | 5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one | | Synonyms: | Nevirapine Related CoMpound A;Nevirapine Related Compound A (15 mg) (5,11-dihydro-6H-11-ethyl-4-methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one);BIRH 414;11-Ethyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one;5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one;11-ethyl-4-methyl-5H-dipyrido[2,3-e:2',3'-f][1,4]diazepin-6-one;Nevirapine EP Impurity A;BIRH 414 BS | | CAS: | 133627-17-5 | | MF: | C14H14N4O | | MW: | 254.29 | | EINECS: | | | Product Categories: | Pharmaceuticals, Intermediates & Fine Chemicals | | Mol File: | 133627-17-5.mol | ![5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Structure](CAS/GIF/133627-17-5.gif) |
| | 5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Chemical Properties |
| Melting point | 212-214℃ (1,2-dichloroethane ) | | Boiling point | 389.8±42.0 °C(Predicted) | | density | 1.224±0.06 g/cm3(Predicted) | | pka | 12.05±0.20(Predicted) |
| | 5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Usage And Synthesis |
| Uses | BIRH 414 is an derivative of 1-[(2-Hydroxyethoxy)methyl]-6-(phenylthio)thymine, a highly potent inhibitor of wild-type human immunodeficiency virus type 1. BIRH 414 was also shown to exhibit binding affinity towards HIV-1 reverse transcriptase enzyme.
This is also an impurity found in Nevirapine (N391275). |
| | 5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Preparation Products And Raw materials |
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