8-Bromoisoquinoline

8-Bromoisoquinoline Basic information

Product Name:	8-Bromoisoquinoline
Synonyms:	8-BROMOISOQUINOLINE;8-Bromoisoquinoline 95%;Isoquinoline, 8-bromo-;8-Bromoisoquinoline ,97%;8-Bromoisoquinoline >;8-BromoisoquinoL;8-Bromoisoquinoline ISO 9001：2015 REACH
CAS:	63927-22-0
MF:	C9H6BrN
MW:	208.05
EINECS:	689-822-4
Product Categories:	Building Blocks;Isoquinoline;Halides;Quinolines, Isoquinolines & Quinoxalines;Quinoline&Isoquinoline;Quinolines, Isoquinolines & Quinoxalines;blocks;Bromides;Heterocyclic Series;Isoquinoline Derivertives;C8 to C10;Chemical Synthesis;Heterocyclic Building Blocks;New Products for Chemical Synthesis;Heterocycles;Quinolines;Quinoline series
Mol File:	63927-22-0.mol

8-Bromoisoquinoline Chemical Properties

Melting point	80,5 C
Boiling point	312.3±15.0 °C(Predicted)
density	1.564±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:8): .5 mg/ml
form	powder to crystal
pka	4.63±0.23(Predicted)
color	Light orange to Yellow to Green
InChIKey	DPRIHFQFWWCIGY-UHFFFAOYSA-N
CAS DataBase Reference	63927-22-0(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi,Xn,T
Risk Statements	36/37/38-20/21/22-25
Safety Statements	26-36-45
RIDADR	2811
Hazard Note	Irritant
HazardClass	6.1
PackingGroup	Ⅲ
HS Code	29334900

MSDS Information

8-Bromoisoquinoline Usage And Synthesis

Chemical Properties	Yellow powder
Uses	8-Bromoisoquinoline is an intermediate used to prepare 4-?((2-?Hydroxy-?3-?methoxybenzyl)?amino)?benzenesulfonamide derivatives as potent and selective inhibitors of 12-?Lipoxygenase. It is also used in the synthesis of selective excitatory amino acid transporter subtype 1 (EAAT1) Inhibitor UCPH-?102.

8-Bromoisoquinoline Preparation Products And Raw materials

Raw materials	Sodium hydroxide-->Hydrochloric acid-->Methanol-->Sulfuric acid-->N,N-Dimethylformamide-->Sodium nitrite-->Triethylamine-->Ammonium hydroxide-->Palladium-->N-Bromosuccinimide-->Potassium iodide-->Phosphorus pentoxide-->Potassium nitrate-->Isoquinoline-->2,2-Diethoxyethylamine-->2-Bromobenzaldehyde
Preparation Products	TERT-BUTYL 8-BROMO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE-->ISOQUINOLINE-8-CARBALDEHYDE

5-nitro-4-bromoisoquinoline 1,8-Dimethyl-5-bromoisoquinoline 5-CHLORO-8-BROMOISOQUINOLINE Isoquinoline 6-BROMOISOQUINOLINE 1-(2-AMINOETHYL)AMINO-4-BROMOISOQUINOLINE 3-AMINO-1-BROMOISOQUINOLINE,1-BROMOISOQUINOLINE-3-AMINE,3-Amino-1-bromoisoquinoline 98% 5-BROMOISOQUINOLINE,5-Bromoisoquinoline,98% 8-BROMO-5-NITRO-ISOQUINOLINE 1-BROMOISOQUINOLINE, 95+%,1-BROMOISOQUINOLINE 1-Chloro-6-bromoisoquinoline 7-BROMOISOQUINOLINE 8-Bromoisoquinoline 5,8-Dibromoisoquinoline 4-Bromoisoquinoline ,98%,4-BROMOISOQUINOLINE 3-Hydroxy-7-bromoisoquinoline 7-BROMOISOQUINOLINE-1(2H)-ONE 1,3-DIBROMOISOQUINOLINE

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