S-adenosylmethionine

S-adenosylmethionine Basic information
Product Name:S-adenosylmethionine
Synonyms:S-ADENOSYLMETHIONINE;5'-[(3-Amino-3-carboxypropyl)methylsulfonio]-5'-deoxyadenosine;5'-Adenosyl(methyl)(3-amino-4-oxo-4-hydroxybutyl)sulfonium;Methionine,active;S-(5'-Adenosyl)methionine;S-Adenosyl-L-methionine sulfate p-toluene sulfonate salt;MEFKEPWMEQBLKI-AIRLBKTGSA-O;13CH3-SAM
CAS:485-80-3
MF:C15H23N6O5S
MW:400.45
EINECS:
Product Categories:
Mol File:485-80-3.mol
S-adenosylmethionine Structure
S-adenosylmethionine Chemical Properties
Safety Information
MSDS Information
S-adenosylmethionine Usage And Synthesis
UsesS-Adenosyl-methionine labelled-15N5 is a useful research chemical. CAS# 485-80-3 is used in ReFlexIn, flexible receptor protein-ligand docking scheme evaluated on HIV-1 protease.
DefinitionChEBI: S-adenosyl-L-methionine is a sulfonium compound that is the S-adenosyl derivative of L-methionine. It is an intermediate in the metabolic pathway of methionine. It has a role as a coenzyme, a nutraceutical, a micronutrient, a human metabolite, a Saccharomyces cerevisiae metabolite, a Mycoplasma genitalium metabolite and a cofactor. It is a conjugate acid of a S-adenosyl-L-methioninate. It is an enantiomer of a S-adenosyl-D-methionine. It is a tautomer of a S-adenosyl-L-methionine zwitterion.
Veterinary Drugs and TreatmentsIn small animal medicine, SAMe is most commonly used as an adjunctive treatment for liver disease (chronic hepatitis, hepatic lipidosis, cholangiohepatitis, feline triad disease, etc.). It may also be of benefit in osteoarthritis, treatment of acute hepatotoxin-induced liver toxicity (e.g., acetaminophen toxicity), and at-risk patients on long-term therapy using drugs with hepatotoxic potential.
In humans, SAMe is being used as a treatment for depression, osteoarthritis, AIDS-related myopathy, intrahepatic cholestasis, liver disease, alcoholic liver cirrhosis, fibromyalgia, adult ADHD, Alzheimer’s, migraines, etc.
S-adenosylmethionine Preparation Products And Raw materials

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