2-MERCAPTO-L-HISTIDINE

2-MERCAPTO-L-HISTIDINE Basic information
Product Name:2-MERCAPTO-L-HISTIDINE
Synonyms:L-THIOHISTIDINE;H-HIS(2-MERCAPTO)-OH;H-2-MERCAPTO-HIS-OH;1H-IMIDAZOLE-4-PROPANOIC ACID;2-MERCAPTO-HISTIDINE;2-MERCAPTO-L-HISTIDINE;2-THIOLHISTIDINE;(S)-alpha-amino-2,3-dihydro-2-thioxo-1H-imidazole-4-propionic acid
CAS:2002-22-4
MF:C6H9N3O2S
MW:187.22
EINECS:217-899-2
Product Categories:Heterocycles;Amino Acids 13C, 2H, 15N;Amino Acids & Derivatives;Sulfur & Selenium Compounds
Mol File:2002-22-4.mol
2-MERCAPTO-L-HISTIDINE Structure
2-MERCAPTO-L-HISTIDINE Chemical Properties
Melting point 320-325°C
Boiling point 376.3±52.0 °C(Predicted)
density 1.52±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility Aqueous Acid (Slightly)
form Solid
pkapK1:1.84(+1);pK2:8.47(0);pK3:11.4(SH) (25°C)
color Off-White
Safety Information
MSDS Information
2-MERCAPTO-L-HISTIDINE Usage And Synthesis
Chemical PropertiesColourless Crystals
UsesAn intermediate in the formation of L-egothioneine, a natural amino acid ubiquitously present in cells and tissues of most plants and mammalian species. In humans, L-ergothioneine is found in red blo od cells, liver, kidney, brain, seminal fluid, and cataract-free lenses at concentrations ranging from 100 uM to 2 mM. L-ergothioneine is exclusively biosynthesized in fungi and mycobacteria. Hence, humans assimilate it through dietary intake.
UsesAn intermediate in the formation of L-egothioneine, a natural amino acid ubiquitously present in cells and tissues of most plants and mammalian species. In humans, L-ergothioneine is found in red blood cells, liver, kidney, brain, seminal fluid, and cataract-free lenses at concentrations ranging from 100 uM to 2 mM. L-ergothioneine is exclusively biosynthesized in fungi and mycobacteria. Hence, humans assimilate it through dietary intake.L-ergothioneine has been proven to act as an antioxidant in vivo and to afford protection from g and UV radiation as well as from singlet oxygen in vivo. Recently, it has been shown that L-ergothioneine protects isolated perfused heart against the deleterious effect of post-ischemic reperfusion.The intermediate, 2-mercaptohistine has been used for the
2-MERCAPTO-L-HISTIDINE Preparation Products And Raw materials
Preparation ProductsL-Histidine
BARIUM THIOSULFATE D-2-Thiolhistidine 2-MERCAPTO-L-HISTIDINE 2-CHLOROMETHYL-5-(4-CHLOROPHENYL)-1,3,4-THIADIAZOLE 2-MERCAPTOIMIDAZOLE L-Histidine L-(+)-Ergothioneine 2-MERCAPTO-L-HISTIDINE METHYL ESTER thiolhistidine betain L-2-Thiolhistidine

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