2-Amino-4-chloropyrimidine

2-Amino-4-chloropyrimidine Basic information

Product Name:	2-Amino-4-chloropyrimidine
Synonyms:	AKOS BBS-00005838;4-CHLOROPYRIMIDIN-2-AMINE;2-PYRIMIDINAMINE, 4-CHLORO-;2-AMINO-4-CHLOROPYRIMIDINE;CHLORO-ISO-CYTOSINE;2-Pyrimidinamine, 4-chloro- (9CI);2-AMINO-4-CHLOROPYRIMIDINE, 98+%;2-Amino-4-chloropyri
CAS:	3993-78-0
MF:	C4H4ClN3
MW:	129.55
EINECS:
Product Categories:	Bases & Related Reagents;Heterocycles;Nucleotides;Pyrazines, Pyrimidines & Pyridazines;Building Blocks;Halogenated Heterocycles;Amines;Pyrazines, Pyrimidines & Pyridazines;Heterocyclic Compounds;Heterocyclic Building Blocks;Pyrimidines;PyrimidinesHeterocyclic Building Blocks;Heterocycle-Pyrimidine series;chloropyrimidin;PYRIMIDINE;APIs & Intermediate;Pyridines, Pyrimidines, Purines and Pteredines
Mol File:	3993-78-0.mol

2-Amino-4-chloropyrimidine Chemical Properties

Melting point	155-160 °C (dec.)
Boiling point	314.6±34.0 °C(Predicted)
density	1.437±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Soluble in dimethyl sulfoxide.
pka	3.55±0.10(Predicted)
form	Solid
color	White
CAS DataBase Reference	3993-78-0(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi,Xn
Risk Statements	36/37/38-41-37/38-22
Safety Statements	26-36/37/39-36/39-60
WGK Germany	3
Hazard Note	Irritant
HS Code	29335990

MSDS Information

2-Amino-4-chloropyrimidine Usage And Synthesis

Chemical Properties	White Solid
Uses	2-Amino-4-chloropyrimidine is a substrate used in a palladium-catalyzed cyanation with zinc(II) cyanide. It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff fields.
Purification Methods	It has also been purified by sublimation in a vacuum and recrystrallisation from H2O. [Hilbert & Johnson J Am Chem Soc 52 1155 1930, Beilstein 24 H 80, 25 III/IV 2117.]

2-Amino-4-chloropyrimidine Preparation Products And Raw materials

Raw materials	Phosphorus oxychloride-->Chlorosulfonic acid-->Isocytosine
Preparation Products	2-AMINO-4-METHOXYPYRIMIDINE-->4-Pyrimidinecarbonitrile, 2-amino- (9CI)-->5-bromo-4-chloropyrimidin-2-amine-->4-((trimethylsilyl)ethynyl)pyrimidin-2-amine-->2-Pyrimidinamine, 4-(6-bromo-2,3-dihydro-1H-indol-1-yl)--->4-(pyrrolidin-1-yl)pyrimidin-2-amine

MCPA SOLUTION 100 NG/MYL IN ACETONITRIL& 2-Amino-6-chloropurine-9-riboside 6-CHLORO-5-NITROPYRIMIDINE-2,4-DIAMINE 2-Amino-6-chloro-4-pyrimidinol 3-[(4-CHLORO-6-METHYLPYRIMIDIN-2-YL)AMINO]-2-(PROPYLSULFONYL)ACRYLONITRILE 2-AMINO-4-CHLORO-6-PHENYLPYRIMIDINE 6-Chloroguanine 4-Chloropyrimidine 2-(4-CHLOROBENZOYL)-3-[(4-CHLORO-6-METHYLPYRIMIDIN-2-YL)AMINO]ACRYLONITRILE 2-Amino-4-chloropyrimidine 6-Aminocaproic acid 3-[(4-CHLORO-6-METHYLPYRIMIDIN-2-YL)AMINO]-2-[(4-CHLOROPHENYL)SULFONYL]ACRYLONITRILE 2-(2-CHLOROBENZOYL)-3-[(4-CHLORO-6-METHYLPYRIMIDIN-2-YL)AMINO]ACRYLONITRILE 2-Aminopyrimidine 2-Anilino-4-chloro-6-methylpyrimidine 3-([(4-CHLORO-6-METHYLPYRIMIDIN-2-YL)AMINO]METHYLIDENE)-1,5,6-TRIMETHYL-1,2,3,4-TETRAHYDRO-2LAMBDA6-THIENO[2,3-C][1,2]THIAZINE-2,2,4-TRIONE Tris(hydroxymethyl)aminomethane AMINO ACIDS

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