Cefteram pivoxil

Cefteram pivoxil Basic information
Product Name:Cefteram pivoxil
Synonyms:CefteramPivoxilCefteramPivoxil;pivaloyloxymethyl (z)-7-[2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido]-3-(5-methyl-2h-tetrazol-2-ylmethyl)-3-cephem-4-carboxylate;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[(5-methyl-2H-tetrazol-2-yl)methyl]-8-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, [6R-[6α,7β(Z)]]-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[(5-methyl-2H-tetrazol-2-yl)methyl]-8-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, (6R,7R)-;Antibiotic T 2588;Ro 19-5248;T 2588;Tomiron
CAS:82547-81-7
MF:C22H27N9O7S2
MW:593.64
EINECS:1312995-182-4
Product Categories:Amines;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
Mol File:82547-81-7.mol
Cefteram pivoxil Structure
Cefteram pivoxil Chemical Properties
Melting point 125-128°C
density 1.3216 (rough estimate)
refractive index 1.7400 (estimate)
storage temp. Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility DMSO: 0.01 mg/mL (0.02 mM);
form Solid
pka8.08±0.60(Predicted)
color White to Pale Yellow
Water Solubility Water: Insoluble
Safety Information
ToxicityLD50 in male, female mice, rats (g/kg): >6.00, 5.86, 5.63, 5.09 i.p.; in both species >6.00 s.c.; in male mice, rats, dogs (g/kg): >6.00, >6.00, >2.00 orally (Sato)
MSDS Information
Cefteram pivoxil Usage And Synthesis
Chemical PropertiesOff-White to Pale Yellow Solid
UsesThird generation, orally active cephalosporin antibiotic. Antibacterial.
DefinitionChEBI: Cefteram pivoxil is a pivaloyloxymethyl ester, a member of cephams, an oxime O-ether, a member of tetrazoles and a member of 1,3-thiazoles.
Cefteram pivoxil Preparation Products And Raw materials
Raw materialsIodomethyl pivalate-->Cefteram pivoxil-->7-Aminocephalosporanic acid
Cefteram pivoxil Cefetamet pivoxyl Cefteram pivoxil Cemandil sodium salt Cefditoren pivoxil Methyl N,N-dimethylaminoacrylate Cefteram pivoxil mesitylenesulfonate Cefteram Pivoxil Oral

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