3-Methoxysalicylic acid

3-Methoxysalicylic acid Basic information
Product Name:3-Methoxysalicylic acid
Synonyms:2-hydroxy-3-methoxy-benzoicaci;2-hydroxy-m-anisicaci;3-Methoxysalicylic acid,97%;3-Methoxysalicylic a;3-Methoxysalicylic acid, 97% 25GR;Guaiacol-3-carboxylic Acid 2-Hydroxy-3-methoxybenzoic Acid o-Vanillic Acid;Benzoic acid,2-hydroxy-3-Methoxy-;2-Hydroxy-3-methoxybenzoic acid, >=99%
CAS:877-22-5
MF:C8H8O4
MW:168.15
EINECS:212-888-9
Product Categories:Organic acids;Miscellaneous;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;BUILDING BLOCKS
Mol File:877-22-5.mol
3-Methoxysalicylic acid Structure
3-Methoxysalicylic acid Chemical Properties
Melting point 147-150 °C(lit.)
Boiling point 217.07°C (rough estimate)
density 1.1816 (rough estimate)
refractive index 1.4611 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka2.85±0.10(Predicted)
form Solid
color Off-White to Beige
BRN 2209642
LogP1.940
CAS DataBase Reference877-22-5(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-20/21/22
Safety Statements 26-37/39-36
WGK Germany 3
RTECS BZ4840000
HS Code 29189900
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
3-Methoxysalicylic acid Usage And Synthesis
Chemical Propertiesbeige powder
Useso-Vanillic Acid, is a derivative of Vanillic Acid (V097350), used as a flavoring agent. o-Vanillic Acid, is also a building block used for the synthesis of more complex pharmaceutical compounds such as Warfarin (W498500), and Phenprocoumon (P318820).
Uses2-Hydroxy-3-methoxybenzoic acid was used as internal standard during the simultaneous quantification of acetylsalicylic acid and its metabolite salicylic acid in human plasma by high-performance liquid chromatography. It was used in large-scale synthesis of 7-methoxy-3(2H)-benzofuranone.
DefinitionChEBI: 3-methoxysalicylic acid is benzoic acid substituted with a hydroxy group at position C-2 and a methoxy group at position C-3. It has a role as a metabolite.
3-Methoxysalicylic acid Preparation Products And Raw materials
Preparation ProductsLY 294002 HYDROCHLORIDE-->1-(2-hydroxy-3-methoxy-phenyl)ethanone-->Methyl 5-allyl-3-methoxysalicylate-->2-Hydroxy-3-methoxybenzyl alcohol-->Benzoyl chloride, 2-hydroxy-3-methoxy- (9CI)
Methylparaben 2,6-Dimethoxybenzoic acid 4-Hydroxybenzoic acid 3-Methoxybenzoic acid 4-Methoxybenzylchloride (+)-Bicuculline 2-HYDROXY-3,4-DIMETHOXYBENZOIC ACID 3-Hydroxybenzoic acid Folic acid 3-Methoxysalicylic acid 2,3,4-Trimethoxybenzoic acid 2,3-Dimethoxybenzoic acid 2,3,4-Trihydroxybenzoic acid p-Anisidine phosphoric acid 3,5-Dinitrosalicylic acid CHLOROPHOSPHONAZO III 5-CARBOXYVANILLIC ACID

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