beta-Bromostyrene

beta-Bromostyrene Basic information
Product Name:beta-Bromostyrene
Synonyms:(2-bromoethenyl)-benzen;1-Bromo-2-phenylethene;Styryl bromide;styrylbromide;2-(BROMOVINYL)BENZENE;OMEGA-BROMOSTYRENE;B-BROMOSTYRENE;B-BROMSTYROL
CAS:103-64-0
MF:C8H7Br
MW:183.05
EINECS:203-131-3
Product Categories:Alkenyl;Building Blocks;Chemical Synthesis;Halogenated Hydrocarbons;Organic Building Blocks;Pharmaceutical Intermediates
Mol File:103-64-0.mol
beta-Bromostyrene Structure
beta-Bromostyrene Chemical Properties
Melting point 7 °C(lit.)
Boiling point 219-221 °C(lit.)
density 1.427 g/mL at 25 °C(lit.)
vapor pressure 16.4Pa at 25℃
refractive index n20/D 1.608
Fp 215 °F
storage temp. 2-8°C
solubility Soluble in alcohol.
form Liquid
color very deep green-yellow
Odorat 1.00 % in dipropylene glycol. strong leafy green hyacinth
Odor Typegreen
Water Solubility 56.624mg/L at 25℃
BRN 2038495
LogP3.391 at 25℃
CAS DataBase Reference103-64-0(CAS DataBase Reference)
NIST Chemistry ReferenceBenzene, (2-bromoethenyl)-(103-64-0)
EPA Substance Registry System.beta.-Bromostyrene (103-64-0)
Safety Information
Hazard Codes Xn
Risk Statements 22
Safety Statements 23-24/25-36/37
WGK Germany 3
RTECS WL3850000
TSCA Yes
HS Code 29039990
Hazardous Substances Data103-64-0(Hazardous Substances Data)
toxicityAn acute oral LD50 in rats was reported as 1.25 ml/kg(0.82-189 ml/kg). The acute dermal LD50 was reported as > 6 ml/kg in the rabbit
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
beta-Bromostyrene Usage And Synthesis
Chemical PropertiesCLEAR YELLOWISH TO BROWN LIQUID
OccurrenceApparently has not been reported to occur in nature.
UsesPerfumery.
UsesBeta-Bromostyrene, cis + trans is an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.
Usesβ-Bromostyrene was used in the one-pot method for the preparation of cinnamonitriles. It was also used in the preparation of pure ethyl Z- and E-α,α-difluoro-4-phenyl-3-butenoate and 1,3-diphenyl-1-butene. It may be used in the synthesis of β-tert-butylstyrene via cross coupling reaction with tert-butylmagnesium chloride in the presence of dichloro[1,1′-bis(diphenylphosphino)ferrocene]nickel(II) catalyst. It may also be used to prepare γ-but-2-enolactone by reacting with nickel carbonyl in the presence of alkynes.
PreparationBy the action of aqueous alkali on cinnamic acid dibromide.
General Descriptionβ-Bromostyrene is an α,β-unsaturated aromatic halide. It can be synthesized by catalytic Hunsdiecker reaction (CHR) of cinnamic acid. It is commonly utilized as a precursor for preparing substituted alkenes, corresponding acetylenes and also in the total synthesis of natural compounds and antibiotics.
Flammability and ExplosibilityNotclassified
beta-Bromostyrene Preparation Products And Raw materials
Raw materialsCinnamyl bromide-->ALPHA-BROMOSTYRENE-->3-Butyn-1-ol
Preparation ProductsPhenylacetylene-->ISOAMYLBENZENE-->CINNAMONITRILE
SPECS AC-907/25004746 AURORA KA-3566 AKOS 92907 N-METHYL-3-BROMO-2(1H)-QUINOLINONE [(Z)-2-Bromoethenyl]benzene Storax oil 3-BROMO-4-HYDROXY-CHROMEN-2-ONE 3-BROMOCOUMARIN AURORA KA-3219 3-bromo-7-hydroxy-4-methyl-2H-chromen-2-one AURORA KA-5227 Styrene-acrylic resin 2-Phenyl-1-propene 2-BROMO-3-(PHENYLAMINO)INDEN-1-ONE AURORA KA-3327 (2-BROMO-1,3,3-TRIPHENYLPROP-1-ENYL)BENZENE bromo-Dragonfly 1-BROMO-2-PHENYL-PROPENE Bromstyrol

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