Isoniazid-D4

Isoniazid-D4 Basic information
Product Name:Isoniazid-D4
Synonyms:Isoniazid-D4;4-Pyridine-2,3,5,6-d4-carboxylic Acid Hydrazide;FSR-3-d;Isonicotinylhydrazine-d4;RP-5015-d4;Tubazid-d4;(4-Pyridine-2,3,5,6-D-carboxylic Acid Hydrazide;FSR-3-d3
CAS:774596-24-6
MF:C6H7N3O
MW:137.14
EINECS:
Product Categories:Amines;Aromatics;Intermediates & Fine Chemicals;Isotope Labeled Compounds;Pharmaceuticals;Isotope Labelled Compounds
Mol File:774596-24-6.mol
Isoniazid-D4 Structure
Isoniazid-D4 Chemical Properties
Melting point 171.40C
storage temp. Refrigerator
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
color White to Pale Beige
Safety Information
MSDS Information
Isoniazid-D4 Usage And Synthesis
Chemical PropertiesCrystalline Solid
UsesLabelled Isoniazid. Antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. Selectively induces expression of CYP2E1. Reversibly inhibits CYP2C19 and CYP3A4 activities, and mechanistically inactivates CYP1A2, CYP2A6, CYP2C19 and CYP3A4 at clinically relevant concentrations. Antibacterial (tuberculostatic).
Isoniazid-D4 Preparation Products And Raw materials
Methyl isonicotinate 3,6-di(4-pyridinyl)-1,4-dihydro-1,2,4,5-tetraazine Isoniazid 2,3'-Bipyridine ISONICOTINOYL CHLORIDE HYDROCHLORIDE 2-Picolinic acid 1,2-Bis(4-pyridylcarbonyl)hydrazine Isoniazid-D4

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