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| | Asiatic acid Basic information |
| Product Name: | Asiatic acid | | Synonyms: | (1s,2r,4as,6ar,6as,6br,8ar,9s,10s,11r,12as,14br)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1h-picene-4a-carboxylic acid;ASIATIC ACID;URS-12-EN-28-OIC ACID, 2,3,23-TRIHYDROXY-, (2A,3B,4A)-;Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, (2.alpha.,3.beta.,4.alpha.)-;ASIATIC ACID(P);Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, (2α,3β,4α)-;ASIATICACID:URS-12-EN-28-OICACID, 2,3,23-TRIHYDROXY-, (2A,3B,4A)-,;2α,3β,23-Trihydroxyurs-12-en-28-oicacid | | CAS: | 464-92-6 | | MF: | C30H48O5 | | MW: | 488.7 | | EINECS: | 482-720-9 | | Product Categories: | Inhibitors;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Antineoplastic;Steroids;The group of Asiaticoside;Pentacyclic Triterpenes;C13 to C42+;Carbonyl Compounds;Carboxylic Acids;464-92-6;API | | Mol File: | 464-92-6.mol |  |
| | Asiatic acid Chemical Properties |
| Melting point | 325-330 °C(lit.) | | Boiling point | 609.4±55.0 °C(Predicted) | | density | 1.18±0.1 g/cm3(Predicted) | | RTECS | YU9580000 | | storage temp. | 2-8°C | | solubility | methanol: soluble1mg/mL, clear, colorless | | pka | 4.66±0.70(Predicted) | | form | powder | | color | white | | Water Solubility | Soluble in dimethyl sulfoxide, ethanol and dimethylformamide. Sparingly soluble in water | | InChIKey | JXSVIVRDWWRQRT-UYDOISQJSA-N | | LogP | 5.748 (est) | | CAS DataBase Reference | 464-92-6(CAS DataBase Reference) |
| | Asiatic acid Usage And Synthesis |
| Uses | wound healing, experimental carcinogen | | Uses | Asiatic Acid is a terpenoid with an ursane skeleton isolated from Centella asiatica. Asiatic Acid is a neuroprotectant and induces of apoptosis in HepG2 human hepatoma cells. | | Uses | Asiatic acid is commonly used in wound healing. Asiatic acid has antioxidant, anti-inflammatory and neuroprotective properties. It is a starting material for asiatic acid derivative synthesis for use as anticancer agents, glycogen phosphorylase inhibitors and and hepatoprotectants. | | Definition | ChEBI: A pentacyclic triterpenoid that is ursane substituted by a carboxy group at position 28 and hydroxy groups at positions 2, 3 and 23 (the 2alpha,3beta stereoisomer). It is isolated from Symplocos lancifolia and
Vateria indica and exhibits anti-angiogenic activity. | | General Description | Asiatic acid is a naturally occurring pentacyclic triterpenoid, obtained from Centella asiatica. | | Biochem/physiol Actions | Asiatic acid is commonly used in wound healing. Asiatic acid has antioxidant, anti-inflammatory and neuroprotective properties. | | target | TNF-α | IFN-γ | IL Receptor | Caspase | p21 | NOS | NADPH-oxidase | NO | HMG-CoA reductase | COX |
| | Asiatic acid Preparation Products And Raw materials |
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