A-METHYL-L-TRYPTOPHAN

A-METHYL-L-TRYPTOPHAN Basic information
Product Name:A-METHYL-L-TRYPTOPHAN
Synonyms:(S)-A-METHYLTRYPTOPHAN;ALPHA-ME-DL-TRYPTOPHAN;ALPHA-METHYL-DL-TRYPTOPHAN;A-METHYL-L-TRYPTOPHAN;DL-2-METHYL-2-AMINO-3-(3-INDOLYL)PROPIONIC ACID;DL-ALPHA-METHYLTRYPTOPHAN;H-ALPHA-ME-DL-TRP-OH;H-DL-(ME)TRP-OH
CAS:153-91-3
MF:C12H14N2O2
MW:218.26
EINECS:
Product Categories:Amino Acids;I - Z;Modified Amino Acids
Mol File:153-91-3.mol
A-METHYL-L-TRYPTOPHAN Structure
A-METHYL-L-TRYPTOPHAN Chemical Properties
Melting point 234 °C(Solv: ethanol, 60% (64-17-5))
Boiling point 444.0±35.0 °C(Predicted)
density 1.314±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Slightly, Heated)
form crystalline
pka2.34±0.10(Predicted)
color light yellow
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
A-METHYL-L-TRYPTOPHAN Usage And Synthesis
Chemical PropertiesWhite to off-white powder
Usesα-methyl-DL-tryptophan is used as a blocker of ATBo, an amino acid transporter whose expression is upregulated in cancer. It is also a substrate or non-transported inhibitor of the amino acid transporter PAT2 (slc36a2).
Biochem/physiol Actionsα-methyl-DL-tryptophan is a blocker of ATBo, an amino acid transporter whose expression is upregulated in cancer.
A-METHYL-L-TRYPTOPHAN Preparation Products And Raw materials
Preparation ProductsFMOC-ALPHA-METHYL-DL-TRYPTOPHAN
ALPHA-METHYL-L-TRYPTOPHAN,α-Methyl-(S)-tryptophan 3-Amino-1,2,3,4-tetrahydrocarbazole-3-carboxylic acid, N1-BOC 3-BOC protected 1-METHYL-D-TRYPTOPHAN ALPHA-METHYL[14C]-L-TRYPTOPHAN FMOC-ALPHA-METHYL-DL-TRYPTOPHAN (S)-N-(Ethoxycarbonyl)-a-methyl-D-tryptophan Methyl Ester 3-Amino-1,2,3,4-tetrahydrocarbazole-3-carboxylic acid, N1-BOC 3-FMOC protected ALPHA-METHYL-DL-TRYPTOPHAN METHYL ESTER 2-ACETAMINDO-2-(7-CHLOROINDOL-3-YLMETHYL)PROPANEDIOIC ACID DIMETHYL ESTER N-BOC-5-METHYL-D-TRYPTOPHAN BOC-6-METHYL-DL-TRYPTOPHAN BOC-5-METHYL-DL-TRYPTOPHAN,N-BOC-5-METHYL-DL-TRYPTOPHAN A-METHYL-L-TRYPTOPHAN BOC-ALPHA-METHYL-DL-TRYPTOPHAN 7-METHYL-L-TRYPTOPHAN (2S,4S)-2-(tert-Butyl)-3-(ethoxycarbonyl)-4-(indol-3-yl-methyl]-4-methyl-1,3-oxazolidin-5-one 4-METHYL-D-TRYPTOPHAN 5-OH-ALPHA-METHYL-L-TRYPTOPHAN,5-HYDROXY-ALPHA-METHYL-L-TRYPTOPHAN

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